Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365825 | 0.88 | IDO1 (0.48) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL365426 | 0.87 | MAPT (0.47) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL366998 | 0.86 | HTT (0.46) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL366461 | 0.86 | HTT (0.46) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL364954 | 0.86 | ALDH1A1 (0.42) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL366737 | 0.86 | IDO1 (0.46) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL365521 | 0.85 | KMT2A (0.43) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL364185 | 0.84 | IDO1 (0.45) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL364787 | 0.82 | KMT2A (0.45) | IDO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL366857 | 0.82 | ALDH1A1 (0.44) | IDO1MAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |