SCHEMBL3647946

SCHEMBL3647946

CCN1CCC(CC(N)=O)CC1.CN1CCN(CC(=O)NC2(c3ccc(Cl)cc3)C(=O)Nc3cc(Cl)cc(Cl)c32)CC1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122945 0.87 GHSR (1.00) GHSR
SCHEMBL122833 0.80 GHSR (1.00) GHSR
SCHEMBL124058 0.80 GHSR (0.80) GHSR
SCHEMBL122516 0.78 GHSR (0.84) GHSR
SCHEMBL124753 0.77 GHSR (0.73) GHSR
SCHEMBL122760 0.76 GHSR (0.80) GHSR
SCHEMBL613042 0.75 GHSR (0.75) GHSR
SCHEMBL123874 0.74 GHSR (1.00) GHSR
SCHEMBL123504 0.74 GHSR (0.61) GHSR
SCHEMBL27927685 0.71 GHSR (0.68) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2188253-A2 INDOL-2-ONE DERIVATIVES DISUBSTITUTED IN THE 3-POSITION, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF Sanofi-Aventis (FR) 2010-05-26 EP claimed
WO-2009056707-A2 INDOL-2-ONE DERIVATIVES DISUBSTITUTED IN THE 3-POSITION, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2009-05-07 WO claimed