Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 15/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124058 | 0.84 | GHSR (0.80) | GHSR | |
| SCHEMBL27927684 | 0.79 | GHSR (0.46) | GHSRALDH1A1TP53MAPT | |
| SCHEMBL3647946 | 0.71 | GHSR (0.76) | GHSR | |
| SCHEMBL124753 | 0.70 | GHSR (0.73) | GHSR | |
| SCHEMBL122760 | 0.69 | GHSR (0.80) | GHSR | |
| SCHEMBL122516 | 0.67 | GHSR (0.84) | GHSR | |
| SCHEMBL122833 | 0.67 | GHSR (1.00) | GHSR | |
| SCHEMBL22018853 | 0.66 | RAB9A (0.50) | GHSREPHX1TP53 | |
| SCHEMBL122725 | 0.66 | GHSR (0.55) | GHSR | |
| SCHEMBL27927691 | 0.63 | ALDH1A1 (0.45) | GHSRALDH1A1TP53MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443076-A | Indol-2-one derivatives disubstituted in position 3, their preparation and their therapeutic application | SANOFI AVENTIS | 2013-12-11 | — | — | CN | claimed |
| CN-103443076-A | Indol-2-one derivatives disubstituted in position 3, their preparation and their therapeutic application | SANOFI AVENTIS | 2013-12-11 | — | — | CN | disclosed |