SCHEMBL364907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10236848	0.83	P2RX3 (0.40)	MRGPRX4SCN9ATDP1
	SCHEMBL367436	0.82	SCN9A (0.46)	MRGPRX4SCN9A
	SCHEMBL15968165	0.77	FOLH1 (0.55)	MRGPRX4RXRARXRBRXRG
	SCHEMBL15543236	0.75	SCN9A (0.67)	MRGPRX4SCN9A
	SCHEMBL30261516	0.74	MRGPRX4 (0.60)	MRGPRX4SCN9ARXRARXRB
	SCHEMBL25298462	0.72	FOLH1 (0.55)	MRGPRX4RXRARXRBRXRG
	SCHEMBL30442197	0.72	FOLH1 (0.55)	MRGPRX4RXRARXRBRXRG
	SCHEMBL4464916	0.70	FOLH1 (0.56)	MRGPRX4RXRARXRBRXRG
	SCHEMBL22481077	0.69	MRGPRX4 (1.00)	MRGPRX4TDP1
	SCHEMBL364456	0.69	SCN9A (0.55)	MRGPRX4SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.