Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | THPO | P40225 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602702 | 0.89 | IDO1 (0.54) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL21048268 | 0.88 | ESR1 (0.50) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL17832171 | 0.87 | ESR1 (0.44) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL21069851 | 0.85 | ESR1 (0.50) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL29111682 | 0.83 | ESR1 (0.46) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL14106841 | 0.83 | ESR1 (0.59) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL7073627 | 0.83 | ESR1 (0.48) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL11366370 | 0.83 | ESR1 (0.59) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL15240610 | 0.83 | ESR1 (0.59) | ESR1ESR2PDCD1CD274HIF1A | |
| Hydrochloric Acid SCHEMBL11240508 | 0.81 | ALOX15 (0.46) | ESR1ESR2PDCD1CD274HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157286-A | Production of 1,2-bis(hydroxyphenyl)ethane-1,2-diols by electrolytic reduction | MONSANTO COMPANY (US) | 1979-06-05 | — | — | US | claimed |
| US-4133729-A | Production of 1,2-bis(hydroxy-phenyl)ethane-1,2-diols by electrolytic reduction | MONSANTO COMPANY (US) | 1979-01-09 | — | — | US | claimed |
| US-4087336-A | Electrolytic reductive coupling of hydroxybenzaldehydes | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | claimed |
| US-4087463-A | COBALT CARBONYL CATALYST | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | claimed |
| US-10766887-B2 | Benzoxazine-based mixture and use thereof | KOLON INDUSTRIES, INC. (KR) | 2020-09-08 | — | — | US | disclosed |
| US-20190169177-A1 | BENZOXAZINE-BASED MIXTURE AND USE THEREOF | KOLON INDUSTRIES, INC. (KR) | 2019-06-06 | — | — | US | disclosed |
| US-9187591-B1 | Polyphenols and high-performance resins from syringaldehyde | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-11-17 | — | — | US | disclosed |
| US-9187591-B1 | Polyphenols and high-performance resins from syringaldehyde | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-11-17 | — | — | US | disclosed |
| US-9127115-B1 | Polyphenols and high-performance resins from syringaldehyde | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-09-08 | — | — | US | disclosed |
| US-9127115-B1 | Polyphenols and high-performance resins from syringaldehyde | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-09-08 | — | — | US | disclosed |
| EP-2067761-B1 | METHOD OF PRODUCING DIOL, POLYDIOL, SECONDARY ALCOHOL OR DIKETONE COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2015-07-08 | — | — | EP | disclosed |
| US-9051414-B1 | Polyphenols and high-performance resins from syringaldehyde | The United States of America as Represented by the Secretary of he Navy (US) | 2015-06-09 | — | — | US | disclosed |
| US-4157286-A | Production of 1,2-bis(hydroxyphenyl)ethane-1,2-diols by electrolytic reduction | MONSANTO COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4133729-A | Production of 1,2-bis(hydroxy-phenyl)ethane-1,2-diols by electrolytic reduction | MONSANTO COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133729-A | Production of 1,2-bis(hydroxy-phenyl)ethane-1,2-diols by electrolytic reduction | MONSANTO COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133729-A | Production of 1,2-bis(hydroxy-phenyl)ethane-1,2-diols by electrolytic reduction | MONSANTO COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4087463-A | COBALT CARBONYL CATALYST | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4087463-A | COBALT CARBONYL CATALYST | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4087336-A | Electrolytic reductive coupling of hydroxybenzaldehydes | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4087336-A | Electrolytic reductive coupling of hydroxybenzaldehydes | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169177-A1 | BENZOXAZINE-BASED MIXTURE AND USE THEREOF | HELZ, GABBR1, CBX7 | ESR1 535/4885ESR2 1073/4885PDCD1 2579/4885 |
| US-10766887-B2 | Benzoxazine-based mixture and use thereof | HELZ, GABBR1, CBX7 | ESR1 535/4885ESR2 1073/4885PDCD1 2579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.