Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18083650 | 0.87 | — | — | |
| SCHEMBL2347902 | 0.87 | GPR84 (0.43) | ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL2349833 | 0.85 | CES2 (0.48) | ALDH1A1TSHR | |
| SCHEMBL3003455 | 0.85 | — | — | |
| SCHEMBL15266237 | 0.85 | CES2 (0.48) | ALDH1A1TSHR | |
| SCHEMBL2352156 | 0.83 | — | — | |
| SCHEMBL20631319 | 0.81 | — | — | |
| SCHEMBL4697756 | 0.79 | — | — | |
| SCHEMBL10051149 | 0.79 | — | — | |
| SCHEMBL11800628 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9326505-B2 | Methods of inhibiting ethylene responses in plants using dicyclopropene compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-05-03 | — | — | US | disclosed |
| US-20140057788-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING DICYCLOPROPENE COMPOUNDS | UNIV NORTH CAROLINA STATE (US) | 2014-02-27 | — | — | US | disclosed |
| US-8592345-B2 | Methods of inhibiting ethylene responses in plants using dicyclopropene compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-11-26 | — | — | US | disclosed |
| EP-2176202-B1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING DICYCLOPROPENE COMPOUNDS | UNIV NORTH CAROLINA STATE (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2511253-A2 | Methods of inhibiting ethylene responses in plants using dicyclopropene compounds | North Carolina State University (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2176202-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING DICYCLOPROPENE COMPOUNDS | North Carolina State University (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20090203801-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING DICYCLOPROPENE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY | 2009-08-13 | — | — | US | disclosed |
| WO-2009002408-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING DICYCLOPROPENE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203801-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING DICYCLOPROPENE COMPOUNDS | ECE1, GABRE, ECE2 | CYP2C19 1731/4885ALDH1A1 4392/4885STAT6 3378/4885 |
| US-20140057788-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING DICYCLOPROPENE COMPOUNDS | ECE1, GABRE, ECE2 | CYP2C19 1731/4885ALDH1A1 4392/4885STAT6 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.