Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | MAOA | P21397 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.34 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.34 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2894915 | 0.85 | CHRM2 (0.43) | MAOBMAOACA2ALPIMAPT | |
| SCHEMBL2896496 | 0.77 | SLC6A4 (0.54) | MAOBMAOACA2ALPIMAPT | |
| SCHEMBL2896498 | 0.77 | SLC6A4 (0.54) | MAOBMAOACA2ALPIMAPT | |
| SCHEMBL12077475 | 0.72 | ACACB (0.42) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL12077477 | 0.72 | ACACB (0.42) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL14860921 | 0.72 | SLC6A2 (0.47) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL4758033 | 0.72 | OPRK1 (0.46) | OPRK1KCNH2OPRM1 | |
| SCHEMBL4758034 | 0.72 | OPRK1 (0.46) | OPRK1KCNH2OPRM1 | |
| SCHEMBL20958389 | 0.72 | SLC6A2 (0.63) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL20958387 | 0.72 | SLC6A2 (0.63) | OPRK1KCNH2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201004-A1 | NOVEL BENZOOXAZOL- AND BENZOOXATHIOL-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009034042-A1 | NOVEL BENZOOXAZOL- AND BENZOOXATHIOL-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2009-03-19 | — | — | WO | disclosed |