Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21974084 | 0.82 | NR4A2 (0.44) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL1232234 | 0.82 | KMT2A (0.66) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL29432255 | 0.81 | KMT2A (0.64) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL3112677 | 0.81 | KMT2A (0.64) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL1119653 | 0.81 | NQO2 (0.50) | KMT2AMEN1METAP2KDM4ENQO2 | |
| SCHEMBL27510182 | 0.79 | NQO2 (0.49) | KMT2AMEN1METAP2KDM4ENQO2 | |
| Methane SCHEMBL9370413 | 0.79 | KMT2A (0.62) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL30318916 | 0.79 | KMT2A (0.62) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL10348934 | 0.78 | NQO2 (0.47) | KMT2AMEN1METAP2KDM4ENQO2 | |
| SCHEMBL4440498 | 0.78 | KMT2A (0.60) | KMT2AMEN1METAP2KDM4EPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191918-A | Halogenated 8-hydroxyquinoline platinum (II) complex and its synthetic method and application | 桂林师范高等专科学校 | 2018-06-22 | — | — | CN | disclosed |
| CN-103079642-A | Nanoparticle-guided radiotherapy | UNIV DENMARK TECH DTU | 2013-05-01 | — | — | CN | disclosed |
| CN-1681791-B | 8-hydroxy quinoline derivatives | PRANA BIOTECHNOLOGY LTD | 2013-03-27 | — | — | CN | disclosed |
| EP-2178842-A2 | 4-BENZYLAMINOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | Abbott GmbH & Co. KG (DE) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009024611-A2 | 4-BENZYLAMINOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | ABBOTT GMBH & CO. KG (DE) | 2009-02-26 | — | — | WO | disclosed |
| CN-1681791-A | 8-hydroxy quinoline derivatives | PRANA BIOTECHNOLOGY LTD (AU) | 2005-10-12 | — | — | CN | disclosed |
| CN-1043344-C | New heterocyclic compounds | KRONSEDER MASCHF KRONES (JP) | 1999-05-12 | — | — | CN | disclosed |