Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | METAP2 | P50579 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112677 | 0.98 | KMT2A (0.64) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL30318916 | 0.96 | KMT2A (0.62) | KMT2AMEN1METAP2KDM4EPLAU | |
| Diethylamine SCHEMBL7880811 | 0.87 | MEN1 (0.56) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL1232234 | 0.84 | KMT2A (0.66) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL28448323 | 0.83 | KDM4E (0.50) | KMT2AMEN1METAP2KDM4E | |
| SCHEMBL29432255 | 0.82 | KMT2A (0.64) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL862522 | 0.79 | PDE3B (0.47) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9701465 | 0.79 | METAP2 (0.52) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL3650316 | 0.79 | KMT2A (0.60) | KMT2AMEN1METAP2KDM4EPLAU | |
| SCHEMBL4440498 | 0.79 | KMT2A (0.60) | KMT2AMEN1METAP2KDM4EPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505565-B1 | QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-27 | — | — | EP | disclosed |