Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.44 |
| ▸ | XPO1 | O14980 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3650316 | 0.82 | KMT2A (0.60) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL1906559 | 0.77 | TSHR (0.44) | NR4A2PARP1MEN1KMT2AALDH1A1 | |
| SCHEMBL27788693 | 0.76 | CCR1 (0.59) | NR4A2L3MBTL1CCR1CCR8ALDH1A1 | |
| SCHEMBL28286097 | 0.75 | CYP2A6 (0.41) | L3MBTL1CCR1CCR8MEN1KMT2A | |
| SCHEMBL24597723 | 0.73 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29750489 | 0.73 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28323815 | 0.73 | PARP1 (0.38) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10700123 | 0.73 | CCR1 (0.60) | NR4A2L3MBTL1CCR1PARP1MAPT | |
| SCHEMBL1467074 | 0.72 | ALDH1A1 (0.59) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2757274 | 0.72 | METAP2 (0.59) | NR4A2XPO1L3MBTL1CCR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140436-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140436-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | F12, F2, CPB1 | NR4A2 4227/4885XPO1 491/4885L3MBTL1 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.