Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612931 | 0.77 | SLC6A4 (0.50) | SLC6A4SLC6A2ADRA2CHTR2COPRM1 | |
| SCHEMBL27956998 | 0.73 | CASR (0.44) | SLC6A4SLC6A2ADRA2CHTR2COPRM1 | |
| SCHEMBL11103452 | 0.70 | ACP3 (0.55) | HTTACP3PNMTALDH1A1EPHX1 | |
| SCHEMBL19943590 | 0.69 | HTR2A (0.69) | SLC6A4SLC6A2ADRA2CHTR2COPRM1 | |
| SCHEMBL16131653 | 0.69 | HTR2A (0.69) | SLC6A4SLC6A2ADRA2CHTR2COPRM1 | |
| Hydrochloric Acid SCHEMBL1491219 | 0.68 | SLC6A2 (0.46) | SLC6A4SLC6A2ADRA2CHTR2COPRM1 | |
| Oxalic Acid SCHEMBL9613902 | 0.68 | SLC6A2 (0.51) | SLC6A4SLC6A2HTR1AALDH1A1MEN1 | |
| SCHEMBL27644695 | 0.68 | SLC1A3 (0.48) | HTR2CHTR2AHTR2BACP3PNMT | |
| SCHEMBL27643978 | 0.68 | SLC1A3 (0.48) | ACP3PNMTALDH1A1EPHX1MEN1 | |
| SCHEMBL3458826 | 0.68 | CES2 (0.55) | ACP3PNMTALDH1A1EPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593422-A1 | PROCESS FOR CINACALCET HYDROCHLORIDE | Hetero Research Foundation (IN) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007954-A1 | PROCESS FOR CINACALCET HYDROCHLORIDE | HETERO RESEARCH FOUNDATION (IN) | 2012-01-19 | — | — | WO | disclosed |