Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | CASR | P41180 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL4612922 | 0.81 | TAAR1 (0.70) | ADRA2CSLC6A2HTR2CSLC6A4OPRM1 | |
| SCHEMBL365289 | 0.78 | TAAR1 (0.79) | HTR2CTAAR1CYP2D6HTR2AHTR2B | |
| SCHEMBL7877410 | 0.78 | ADRA2C (0.51) | ADRA2CSLC6A2HTR2CSLC6A4OPRM1 | |
| Hydrochloric Acid SCHEMBL12520854 | 0.77 | TAAR1 (0.77) | ADRA2CSLC6A2HTR2CSLC6A4OPRM1 | |
| SCHEMBL1419866 | 0.74 | TAAR1 (0.77) | HTR2CTAAR1CYP2D6HTR2AHTR2B | |
| SCHEMBL2095840 | 0.73 | TAAR1 (0.74) | HTR2CTAAR1CYP2D6HTR2AHTR2B | |
| SCHEMBL6235879 | 0.73 | TAAR1 (0.74) | HTR2CTAAR1CYP2D6HTR2AHTR2B | |
| SCHEMBL28313934 | 0.71 | KDM4E (0.47) | MAPTL3MBTL1SCN5ASCN2A | |
| SCHEMBL4753946 | 0.71 | ADRA2C (0.46) | ADRA2CSLC6A2HTR2CSLC6A4OPRM1 | |
| SCHEMBL50651 | 0.71 | NR4A1 (0.65) | CYP2D6MAPTL3MBTL1HDAC8MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593422-A1 | PROCESS FOR CINACALCET HYDROCHLORIDE | Hetero Research Foundation (IN) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007954-A1 | PROCESS FOR CINACALCET HYDROCHLORIDE | HETERO RESEARCH FOUNDATION (IN) | 2012-01-19 | — | — | WO | disclosed |