Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807998 | 0.79 | PGD (0.43) | PGDSLC22A6SMN1; SMN2TSHRMAPT | |
| SCHEMBL4806982 | 0.79 | PGD (0.43) | PGDSLC22A6SMN1; SMN2TSHRMAPT | |
| SCHEMBL667280 | 0.79 | PGD (0.50) | PGDSLC22A6SMN1; SMN2HMGCRCHRM1 | |
| SCHEMBL6803525 | 0.79 | PGD (0.50) | PGDSLC22A6SMN1; SMN2HMGCRCHRM1 | |
| SCHEMBL6805671 | 0.79 | PGD (0.50) | PGDSLC22A6SMN1; SMN2HMGCRCHRM1 | |
| SCHEMBL5464437 | 0.77 | OR51E2 (0.38) | PGDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL29875674 | 0.77 | TSHR (0.40) | PGDSLC22A6SMN1; SMN2HMGCRCHRM1 | |
| Ammonia Solution, Strong SCHEMBL27881579 | 0.77 | PGD (0.48) | PGDSLC22A6SMN1; SMN2HMGCRCHRM1 | |
| SCHEMBL3646440 | 0.77 | TSHR (0.50) | PGDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL249850 | 0.75 | TSHR (0.39) | PGDSLC22A6SMN1; SMN2HMGCRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0961795-A1 | ACID FUNCTIONALIZED POLYURETHANE ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1999-12-08 | — | — | EP | claimed |
| WO-1998037113-A1 | ACID FUNCTIONALIZED POLYURETHANE ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1998-08-27 | — | — | WO | claimed |
| US-20210139390-A1 | PRODUCTION METHOD OF ORGANIC COMPOUND | UNITIKA LTD. (JP) | 2021-05-13 | — | — | US | disclosed |
| EP-3819283-A1 | METHOD FOR PRODUCING ORGANIC COMPOUND | Unitika Ltd. (JP) | 2021-05-12 | — | — | EP | disclosed |
| EP-2178846-A1 | ROSUVASTATIN INTERMEDIATES AND THEIR PREPARATION | Teva Pharmaceutical Industries Ltd. (IL) | 2010-04-28 | — | — | EP | disclosed |
| US-20090069563-A1 | Rosuvastatin intermediates and their preparation | TEVA PHARMACEUTICALS USA, INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2009009152-A1 | ROSUVASTATIN INTERMEDIATES AND THEIR PREPARATION | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-01-15 | — | — | WO | disclosed |
| US-6610629-B2 | Process for producing an oxide catalyst for oxidation or ammoxidation | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-08-26 | — | — | US | disclosed |
| US-20030017944-A1 | Process for producing an oxide catalyst for oxidation or ammoxidation | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-0961795-A1 | ACID FUNCTIONALIZED POLYURETHANE ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1999-12-08 | — | — | EP | disclosed |
| US-5936055-A | Acid functionalized polyurethane adducts | THE DOW CHEMICAL COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1998037113-A1 | ACID FUNCTIONALIZED POLYURETHANE ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1998-08-27 | — | — | WO | disclosed |
| EP-0168480-A4 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 4-AMINO-3-HYDROXYBUTYRIC ACID. | WISCONSIN ALUMNI RES FOUND (US) | 1987-10-08 | — | — | EP | disclosed |
| US-4584270-A | ENZYME CLEAVAGE OF ESTER GROUPING OF 3-HYDROXYGLUTARIC ACID DIESTER, FOLLOWED BY CHEMICAL CONVERSION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0168480-A1 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 4-AMINO-3-HYDROXYBUTYRIC ACID | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1986-01-22 | — | — | EP | disclosed |
| WO-1985003307-A1 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 4-AMINO-3-HYDROXYBUTYRIC ACID | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069563-A1 | Rosuvastatin intermediates and their preparation | HMGCR, PCSK9, PCSK7 | PGD 965/4885SLC22A6 2065/4885SMN1; SMN2 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.