Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667280 | 1.00 | PGD (0.50) | PGDSLC22A6TSHRSMN1; SMN2MAPT | |
| SCHEMBL6805671 | 1.00 | PGD (0.50) | PGDSLC22A6TSHRSMN1; SMN2MAPT | |
| Ammonia Solution, Strong SCHEMBL27881579 | 0.97 | PGD (0.48) | PGDSLC22A6TSHRSMN1; SMN2MAPT | |
| SCHEMBL6448085 | 0.83 | ALDH1A1 (0.46) | PGDTSHRTDP1CYP2C19 | |
| SCHEMBL6448088 | 0.83 | ALDH1A1 (0.46) | PGDTSHRTDP1CYP2C19 | |
| SCHEMBL14962078 | 0.80 | SLC22A6 (0.52) | PGDSLC22A6TSHRSMN1; SMN2MAPT | |
| SCHEMBL3650683 | 0.79 | PGD (0.47) | PGDSLC22A6TSHRSMN1; SMN2MAPT | |
| SCHEMBL25660449 | 0.79 | PGD (0.47) | PGDSLC22A6SMN1; SMN2MAPTGABRR1 | |
| SCHEMBL6462796 | 0.77 | PGD (0.46) | PGDSLC22A6SMN1; SMN2MAPTGABRR1 | |
| SCHEMBL2467277 | 0.76 | TSHR (0.43) | PGDTSHRLMNATDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087569-A1 | N-heterocyclic bicyclic lactone compounds | NELSON TODD D (US) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087569-A1 | N-heterocyclic bicyclic lactone compounds | VIP, NGLY1, NPPA | PGD 1527/4885SLC22A6 933/4885TSHR 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.