Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654942 | 0.84 | LMNA (0.43) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3653094 | 0.84 | LMNA (0.43) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3041876 | 0.82 | LMNA (0.47) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL1359643 | 0.78 | LMNA (0.55) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL5685875 | 0.74 | CYP2C19 (0.54) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3786684 | 0.74 | CYP2C19 (0.33) | LMNACYP2C19HIF1A | |
| SCHEMBL11005886 | 0.74 | CYP2C19 (0.52) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL2011397 | 0.72 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL16875799 | 0.72 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL622562 | 0.71 | LMNA (0.48) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200971-A1 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2010-06-30 | — | — | EP | claimed |
| WO-2009047316-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-04-16 | — | — | WO | claimed |