Biphenyl

Biphenyl

SCHEMBL3652128

[IH2+].c1ccc(-c2ccccc2)cc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
MAPK1 P28482 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
HSD17B10 Q99714 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NOTUM Q6P988 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
ATM Q13315 1/20 0.39
SLC22A2 O15244 1/20 0.39
SLC22A1 O15245 1/20 0.39
SLC22A3 O75751 1/20 0.39
SLC6A4 P31645 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MAOA P21397 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225363 0.93 ALDH1A1 (0.47) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2
SCHEMBL19977300 0.90 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2
SCHEMBL19977298 0.90 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2
SCHEMBL24518243 0.90 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2
SCHEMBL19977293 0.90 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2
SCHEMBL24518410 0.90 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2
SCHEMBL11707018 0.89 ALDH1A1 (0.50) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2
Benzene SCHEMBL31091106 0.89 ALDH1A1 (0.50) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2
SCHEMBL143876 0.89 ALDH1A1 (0.50) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2
SCHEMBL17417851 0.88 ALDH1A1 (0.53) ALDH1A1MAPK1TAAR1HSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2212746-A1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE Agfa Graphics N.V. (BE) 2010-08-04 EP disclosed
WO-2009063024-A1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2009-05-22 WO disclosed
US-20080044767-A1 NEGATIVE-WORKING IMAGEABLE MATERIALS KODAK (NEAR EAST) INC. 2008-02-21 US disclosed