SCHEMBL19977293

SCHEMBL19977293

c1ccc(-c2ccc([B-](c3ccccc3)(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TAAR1 Q96RJ0 2/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP1A2 P05177 2/20 0.48
MAPK1 P28482 1/20 0.48
CYP3A4 P08684 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
MGLL Q99685 1/20 0.42
KIF11 P52732 1/20 0.42
NOTUM Q6P988 1/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
HSP90AA1 P07900 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24518410 1.00 ALDH1A1 (0.56) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1
SCHEMBL19977298 1.00 ALDH1A1 (0.56) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1
SCHEMBL19977300 1.00 ALDH1A1 (0.56) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1
SCHEMBL24518243 1.00 ALDH1A1 (0.56) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1
SCHEMBL17417851 0.97 ALDH1A1 (0.53) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1
SCHEMBL14142668 0.97 ALDH1A1 (0.60) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1
Potassium Ion SCHEMBL2467134 0.94 ALDH1A1 (0.56) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1
SCHEMBL1173601 0.94 ALDH1A1 (0.56) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1
Biphenyl SCHEMBL3652128 0.90 ALDH1A1 (0.60) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1
SCHEMBL143876 0.87 ALDH1A1 (0.50) ALDH1A1TAAR1HSD17B10CYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180081272-A1 THERMAL CROSSLINKING ACCELERATOR, POLYSILOXANE-CONTAINING RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SAME, AND PATTERNING PROCESS USING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-22 US disclosed