SCHEMBL506811

SCHEMBL506811

FC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
TSHR P16473 2/20 0.37
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
THRB P10828 1/20 0.33
CA2 P00918 1/20 0.31
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64077 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB
SCHEMBL815447 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB
SCHEMBL817697 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB
SCHEMBL735601 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB
SCHEMBL716297 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB
SCHEMBL506073 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB
SCHEMBL816970 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB
SCHEMBL817265 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB
SCHEMBL815543 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB
SCHEMBL61566 1.00 LMNA (0.40) LMNATSHRKDM4ETDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117303378-A Organic-inorganic functional hybrid silica sol and preparation method and application thereof 重庆市地质矿产勘查开发局208水文地质工程地质队(重庆市地质灾害防治工程勘查设计院) 2023-12-29 CN claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
US-6582896-B1 High Dmax (maximum density), a low fog, a good coated surface condition, and less surface defects such as repellency, coating lines or the like. FUJI PHOTO FILM CO., LTD. (JP) 2003-06-24 US claimed
US-6280749-B1 FOR USE IN PAINTS, SYNTHETIC RESINS, SYNTHETIC AND NATURAL RUBBERS, POLISHING AGENTS, SURFACE-RELEASE AGENTS AND COSMETIC OR TOILETRY PREPARATIONS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-28 US claimed
US-20240158551-A1 FLUORORESIN TOSOH CORPORATION (JP) 2024-05-16 US disclosed
CN-118043728-A Spectacle lens, stain-proofing agent composition, and method for producing spectacle lens 豪雅镜片泰国有限公司 2024-05-14 CN disclosed
WO-2024053720-A1 NUCLEIC ACID FOR TRANSFECTION AGC株式会社 2024-03-14 WO disclosed
EP-4306572-A1 POLYMER HAVING HALOGEN-CONTAINING SEGMENT AND PHARMACEUTICAL COMPOSITION USING SAME AGC INC. (JP) 2024-01-17 EP disclosed
US-20240009224-A1 ACYCLIC THREONINOL NUCLEIC ACID THE UNIVERSITY OF TOKYO (JP) 2024-01-11 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed
US-4836958-A SURFACTANT CIBA-GEIGY CORPORATION (US) 1989-06-06 US disclosed
EP-0256980-A2 Fluorinated cationic compounds CIBA-GEIGY AG (CH) 1988-02-24 EP disclosed
EP-0185242-A2 Copolymers of chlorotrifluoroethylene, ethylene and perfluoroalkylethylenes AUSIMONT, U.S.A. (US) 1986-06-25 EP disclosed
EP-0002004-B1 PROCESS FOR THE MANUFACTURE OF FLUORINATED CATIONIC COMPOUNDS AND THEIR USE AS SURFACTANTS CIBA-GEIGY AG (CH) 1982-03-24 EP disclosed
EP-0002004-A1 Process for the manufacture of fluorinated cationic compounds and their use as surfactants CIBA-GEIGY AG (CH) 1979-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 LMNA 178/4885TSHR 4680/4885KDM4E 1868/4885
US-20240009224-A1 ACYCLIC THREONINOL NUCLEIC ACID NSUN2, TRDMT1, SLC29A2 LMNA 111/4885TSHR 2563/4885KDM4E 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.