Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364902 | 0.92 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL366244 | 0.91 | PSEN1 (0.41) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL365511 | 0.91 | KMT2A (0.39) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL367540 | 0.90 | PSEN1 (0.45) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL365365 | 0.89 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL366935 | 0.89 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL364973 | 0.89 | KMT2A (0.42) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL366392 | 0.89 | PSEN1 (0.46) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL366118 | 0.88 | KDM4E (0.45) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL364626 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |