Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 7/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15368987 | 0.84 | TDO2 (0.40) | GPR119KDM4ENPC1RAB9ALMNA | |
| SCHEMBL1093760 | 0.84 | GPR119 (0.48) | GPR119 | |
| SCHEMBL3651096 | 0.83 | GPR119 (0.39) | CYP4F2CYP4A11GPR119KDM4ENPC1 | |
| SCHEMBL1093368 | 0.83 | GPR119 (0.51) | CYP4F2CYP4A11GPR119 | |
| SCHEMBL1093432 | 0.83 | GPR119 (0.49) | GPR119 | |
| SCHEMBL11956895 | 0.82 | KDM1A (0.45) | KDM1AEP300 | |
| SCHEMBL1092853 | 0.81 | KDM4E (0.51) | CYP4F2CYP4A11GPR119KDM4ENPC1 | |
| SCHEMBL1092996 | 0.80 | GPR119 (0.47) | GPR119 | |
| SCHEMBL1092772 | 0.80 | GPR119 (0.64) | GPR119 | |
| SCHEMBL1093429 | 0.79 | GPR119 (0.52) | GPR119KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197873-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009038974-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-03-26 | — | — | WO | disclosed |