SCHEMBL3654045

SCHEMBL3654045

NC(=O)[C@@H](OP(=O)(O)O)[C@@H](OP(=O)(O)O)[C@@H](CO)OP(=O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PGD P52209 1/20 0.33
PTPN1 P18031 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8063785 1.00 PGD (0.33) PGDPTPN1CA4
SCHEMBL6350847 0.80 PTPN1 (0.37) PTPN1
SCHEMBL8071706 0.79 PGD (0.32) PGDPTPN1
SCHEMBL8445428 0.79
SCHEMBL8445386 0.76 MEN1 (0.31)
SCHEMBL8077133 0.70 MAPT (0.39)
SCHEMBL321587 0.69 MPI (0.32) PTPN1
SCHEMBL9737806 0.69 MPI (0.32) PTPN1
SCHEMBL9736063 0.69 MPI (0.32) PTPN1
SCHEMBL9737459 0.69 MPI (0.32) PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2187892-A1 METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA Bioneris AB (SE) 2010-05-26 EP claimed
WO-2009038533-A1 METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA BIONERIS AB (SE) 2009-03-26 WO claimed
JP-2005537105-A 2005-12-08 JP claimed
EP-1545643-A1 COATED STENT Bioneris AB, (SE) 2005-06-29 EP claimed
WO-2004022123-A1 COATED STENT BIONERIS AB (SE) 2004-03-18 WO claimed
EP-0910383-A1 THE USE OF GROWTH FACTOR MODULATING COMPOUNDS PERSTORP AB (SE) 1999-04-28 EP claimed
WO-1997049408-A1 THE USE OF GROWTH FACTOR MODULATING COMPOUNDS PERSTORP AB (SE) 1997-12-31 WO claimed
EP-1545643-A1 COATED STENT Bioneris AB, (SE) 2005-06-29 EP disclosed
WO-2004022123-A1 COATED STENT BIONERIS AB (SE) 2004-03-18 WO disclosed
EP-1023301-A1 A HETEROCYCLIC CHEMICAL COMPOUND PERSTORP AB (SE) 2000-08-02 EP disclosed
EP-0910383-A1 THE USE OF GROWTH FACTOR MODULATING COMPOUNDS PERSTORP AB (SE) 1999-04-28 EP disclosed
WO-1997049408-A1 THE USE OF GROWTH FACTOR MODULATING COMPOUNDS PERSTORP AB (SE) 1997-12-31 WO disclosed
WO-1997018220-A1 A HETEROCYCLIC CHEMICAL COMPOUND PERSTORP AB (SE) 1997-05-22 WO disclosed