Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 6/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653539 | 0.80 | CA12 (0.47) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8071706 | 0.80 | PGD (0.32) | — | |
| SCHEMBL3654045 | 0.70 | PGD (0.33) | — | |
| SCHEMBL8063785 | 0.70 | PGD (0.33) | — | |
| SCHEMBL6350847 | 0.69 | PTPN1 (0.37) | — | |
| SCHEMBL9811910 | 0.68 | POLB (0.55) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL21056246 | 0.66 | MEN1 (0.61) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL4280637 | 0.66 | LPAR1 (0.37) | TSHR | |
| SCHEMBL23066886 | 0.65 | LAP3 (0.46) | HPGDTSHR | |
| SCHEMBL28548192 | 0.65 | POLB (0.55) | MAPTALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023301-A1 | A HETEROCYCLIC CHEMICAL COMPOUND | PERSTORP AB (SE) | 2000-08-02 | — | — | EP | disclosed |
| WO-1997018220-A1 | A HETEROCYCLIC CHEMICAL COMPOUND | PERSTORP AB (SE) | 1997-05-22 | — | — | WO | disclosed |