SCHEMBL3654444

SCHEMBL3654444

CC(=O)OCCCCOc1ccc(C(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.71
POLB P06746 1/20 0.70
APEX1 P27695 1/20 0.70
TDP1 Q9NUW8 1/20 0.70
TSHR P16473 2/20 0.68
TP53 P04637 1/20 0.68
PLA2G4B P0C869 6/20 0.66
L3MBTL1 Q9Y468 1/20 0.62
RARB P10826 4/20 0.62
PKM P14618 1/20 0.61
GAA P10253 1/20 0.61
USP2 O75604 1/20 0.59
ALOX15 P16050 1/20 0.59
MAPK1 P28482 1/20 0.59
HSD17B10 Q99714 1/20 0.59
PLA2G4A P47712 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9435858 0.91 PKM (0.68) HTTPOLBAPEX1TDP1TSHR
SCHEMBL1952122 0.87 TP53 (0.79) HTTPOLBAPEX1TDP1TSHR
SCHEMBL22525345 0.87 RARB (0.64) HTTPOLBAPEX1TDP1TSHR
SCHEMBL27516549 0.87 RARB (0.64) HTTPOLBAPEX1TDP1TSHR
SCHEMBL15084279 0.86 GAA (0.66) HTTPOLBAPEX1TDP1TSHR
SCHEMBL2181009 0.85 TP53 (0.82) HTTPOLBAPEX1TDP1TSHR
SCHEMBL14097198 0.85 TP53 (0.82) HTTPOLBAPEX1TDP1TSHR
SCHEMBL209561 0.85 TP53 (0.82) HTTPOLBAPEX1TDP1TSHR
SCHEMBL2180731 0.85 TP53 (0.82) HTTPOLBAPEX1TDP1TSHR
SCHEMBL7911508 0.85 TP53 (0.82) HTTPOLBAPEX1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159827-A1 LIQUID CRYSTAL COMPOSITION, FLUORINE-CONTAINING POLYMER, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-9364424-B2 Topical cosmetic skin lightening compositions and methods of use thereof STIEFEL LABORATORIES, INC. (US) 2016-06-14 US disclosed
US-20160074315-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. 2016-03-17 US disclosed
EP-2219600-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. (US) 2010-08-25 EP disclosed
WO-2009067095-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. (US) 2009-05-28 WO disclosed
EP-1602354-B1 Use of polyglutamic acid or its salts MEIJI SEIKA KAISHA (JP) 2008-11-05 EP disclosed
EP-1604647-B1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof CHISSO CORP (JP) 2008-05-07 EP disclosed
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair MEIJI SEIKA KAISHA, LTD. (JP) 2006-07-27 US disclosed
US-20060018867-A1 Cosmetic composition and production thereof ICHIMARU PHARCOS CO., LTD 2006-01-26 US disclosed
EP-1604647-A1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof Ichimaru Pharcos Co., Ltd. (JP) 2005-12-14 EP disclosed
EP-1602354-A1 HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR Meiji Seika Kaisha, Ltd. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair CUTA, COL14A1, PRKDC HTT 22/4885POLB 242/4885APEX1 2035/4885
US-20060018867-A1 Cosmetic composition and production thereof CUTA, PARG, TYR HTT 2960/4885POLB 27/4885APEX1 930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.