Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.48 |
| ▸ | SCN2B | O60939 | 6/20 | 0.46 |
| ▸ | SCN1B | Q07699 | 6/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.46 |
| ▸ | SCN1A | P35498 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366723 | 0.79 | MAPT (0.45) | — | |
| SCHEMBL365476 | 0.78 | SCN9A (0.46) | SCN9ASCN2BSCN1BSCN5ASCN1A | |
| SCHEMBL6851190 | 0.76 | BAZ2B (0.45) | — | |
| SCHEMBL366783 | 0.74 | SCN9A (0.54) | SCN9ASCN2BSCN1BSCN5ASCN1A | |
| SCHEMBL366353 | 0.72 | SCN9A (0.49) | SCN9ASCN2BSCN1BSCN5ASCN1A | |
| SCHEMBL6413783 | 0.70 | CHRNA7 (0.39) | — | |
| SCHEMBL6415487 | 0.70 | CHRNA7 (0.58) | — | |
| SCHEMBL14195575 | 0.69 | SMN1; SMN2 (0.44) | SCN9ASCN2BSCN1BSCN5ASCN1A | |
| SCHEMBL6411859 | 0.69 | F10 (0.39) | — | |
| SCHEMBL6417462 | 0.69 | KHK (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |