Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.46 |
| ▸ | SCN2B | O60939 | 8/20 | 0.46 |
| ▸ | SCN1B | Q07699 | 8/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 7/20 | 0.46 |
| ▸ | SCN1A | P35498 | 6/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366724 | 0.79 | CHRNA7 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL365475 | 0.78 | SCN9A (0.48) | SCN9ASCN2BSCN1BSCN5ASCN1A | |
| SCHEMBL6851185 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL366784 | 0.72 | SCN9A (0.50) | SCN9ASCN2BSCN1BSCN5ASCN1A | |
| SCHEMBL366354 | 0.70 | SCN9A (0.46) | SCN9ASCN2BSCN1BSCN5ASCN1A | |
| SCHEMBL6412569 | 0.69 | CHRNA7 (0.84) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL6417457 | 0.68 | CHRNA7 (0.49) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL364110 | 0.68 | HDAC3 (0.58) | SCN9ASCN2BSCN1BSCN5ASCN1A | |
| SCHEMBL28531553 | 0.67 | CHRNA7 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL366978 | 0.67 | SCN9A (0.45) | SCN9ASCN2BSCN1BSCN5ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |