Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 8/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851190 | 0.84 | BAZ2B (0.45) | MAPTALDH1A1BAZ2BBAZ2ACYP1A2 | |
| SCHEMBL365475 | 0.79 | SCN9A (0.48) | — | |
| SCHEMBL366724 | 0.73 | CHRNA7 (0.43) | MAPTALDH1A1HPGDL3MBTL1KMT2A | |
| SCHEMBL17397158 | 0.72 | MAPT (0.42) | MAPTALDH1A1HPGDBAZ2BBAZ2A | |
| SCHEMBL64923 | 0.72 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDL3MBTL1KMT2A | |
| SCHEMBL30307422 | 0.72 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDL3MBTL1KMT2A | |
| SCHEMBL367568 | 0.71 | ALDH1A1 (0.44) | MAPTALDH1A1HPGDBAZ2BBAZ2A | |
| SCHEMBL366735 | 0.71 | HTT (0.48) | MAPTALDH1A1HPGDBAZ2BBAZ2A | |
| Maleic Acid SCHEMBL11114411 | 0.70 | L3MBTL1 (0.47) | MAPTALDH1A1HPGDL3MBTL1KMT2A | |
| Fumaric Acid SCHEMBL11114413 | 0.70 | L3MBTL1 (0.47) | MAPTALDH1A1HPGDL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |