Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 8/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | HTR1E | P28566 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660456 | 0.97 | CDK7 (0.37) | CDK7CDK9FLT3KDRGSK3B | |
| SCHEMBL3660344 | 0.92 | CDK7 (0.36) | CDK7CDK9FLT3KDRGSK3B | |
| SCHEMBL3653965 | 0.78 | HTR1D (0.41) | CDK7CDK9FLT3KDRGSK3B | |
| SCHEMBL3221635 | 0.77 | JAK2 (0.45) | CDK7CDK9FLT3KDRGSK3B | |
| SCHEMBL3657163 | 0.76 | JAK3 (0.36) | CDK7CDK9FLT3KDRGSK3B | |
| SCHEMBL3622286 | 0.76 | FLT3 (0.35) | CDK7CDK9FLT3KDRGSK3B | |
| SCHEMBL3206667 | 0.74 | JAK2 (0.48) | CDK7CDK9FLT3KDRGSK3B | |
| SCHEMBL3225505 | 0.71 | JAK2 (0.46) | CDK7CDK9FLT3KDRGSK3B | |
| SCHEMBL3217678 | 0.70 | CDK7 (0.45) | CDK7CDK9JAK2JAK1HTR1D | |
| SCHEMBL7543009 | 0.68 | MAPK11 (0.50) | CDK7CDK9FLT3KDRGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024980-A1 | 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-03-04 | — | — | WO | disclosed |