Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546199 | 0.81 | MAPK11 (0.50) | MAPK11MAPK14CDK9FLT3SLC6A4 | |
| SCHEMBL7567570 | 0.76 | MAPK11 (0.55) | MAPK11MAPK14CDK7CDK9SLC6A4 | |
| SCHEMBL3216107 | 0.75 | CDK9 (0.39) | CDK7CDK9SLC6A4PARP1 | |
| SCHEMBL2064461 | 0.75 | CDK7 (0.39) | CDK7CDK9FLT3SLC6A4PRKD3 | |
| SCHEMBL3206033 | 0.75 | CDK9 (0.39) | CDK7CDK9FLT3SLC6A4KDM4E | |
| SCHEMBL5850081 | 0.70 | MAPK11 (0.81) | MAPK11MAPK14GSK3BPARP1 | |
| SCHEMBL3627711 | 0.70 | SLC6A4 (0.64) | SLC6A4HTR1AHTR6KDM4ELMNA | |
| SCHEMBL7001878 | 0.69 | MAPK11 (0.48) | MAPK11MAPK14SLC6A4 | |
| SCHEMBL3206667 | 0.69 | JAK2 (0.48) | CDK7CDK9FLT3HTR1AKDR | |
| SCHEMBL7855936 | 0.68 | MAPK11 (0.41) | MAPK11MAPK14SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204662-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS Allelix Corp. (CA) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012629-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS ALLELIX CORP. (US) | 2001-02-22 | — | — | WO | disclosed |