Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | NT5E | P21589 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.69 |
| ▸ | DPP4 | P27487 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.69 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.69 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.69 |
| ▸ | GAPDH | P04406 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | STAT6 | P42226 | 1/20 | 0.69 |
| ▸ | PI4KA | P42356 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fludarabine SCHEMBL14031844 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B | |
| Fludarabine SCHEMBL5505924 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B | |
| Fludarabine SCHEMBL12232219 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B | |
| Fludarabine SCHEMBL977919 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B | |
| Fludarabine SCHEMBL12018226 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B | |
| Fludarabine SCHEMBL12019517 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B | |
| Fludarabine SCHEMBL1981701 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B | |
| Fludarabine SCHEMBL3047091 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B | |
| Fludarabine SCHEMBL6882489 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B | |
| Fludarabine SCHEMBL13046076 | 1.00 | LMNA (1.00) | LMNANT5EHIF1AADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763049-B1 | NUCLEOSIDE MONOPHOSPHATE DERIVATIVES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS IMMUNOSUPPRESSIVE DRUGS | HEIDELBERG PHARMA HOLDING GMBH (DE) | 2003-04-02 | — | — | EP | claimed |
| US-5602246-A | Process for the preparation of fludarabine or fludarabine phosphate from guanosine | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | claimed |
| EP-4653017-A1 | ANTIBODY-DRUG CONJUGATE AND USE THEREOF | Tyligand Bioscience (Shanghai) Limited (CN) | 2025-11-26 | — | — | EP | disclosed |
| CN-118873678-A | Antibody-conjugated drugs and uses thereof | 泰励生物科技（上海）有限公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-2024153127-A1 | ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 泰励生物科技（上海）有限公司 | 2024-07-25 | — | — | WO | disclosed |
| WO-2024152052-A1 | COMPOSITIONS COMPRISING FLUDARABINE PHOSPHATE AND METHODS OF MAKING AND USING SAME TO TREAT CANCER | AREVA PHARMACEUTICALS INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| EP-4399294-A1 | GUIDE RNAS WITH CHEMICAL MODIFICATION FOR PRIME EDITING | Agilent Technologies, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2024129779-A1 | INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION | MODERNATX, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-117467726-B | Preparation method of purine nucleoside | 天津凯莱英生物科技有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117677699-A | Optimized anti-FLT 1 oligonucleotide compounds for treating preeclampsia and other angiogenic disorders | 马萨诸塞大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-117642508-A | Oligonucleotides for IFN-gamma signaling pathway modulation | 马萨诸塞大学 | 2024-03-01 | — | — | CN | disclosed |
| EP-0670845-A1 | PROCESS FOR THE PREPARATION OF FLUDARABINE PHOSPHATE FROM GUANOSINE | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-09-13 | — | — | EP | disclosed |
| EP-0614462-A1 | NEW METHOD OF PREPARING 2-FLUOROPURINE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-09-14 | — | — | EP | disclosed |
| WO-1994012514-A1 | PROCESS FOR THE PREPARATION OF FLUDARABINE PHOSPHATE FROM GUANOSINE | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-06-09 | — | — | WO | disclosed |
| EP-0355135-B1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1993-08-04 | — | — | EP | disclosed |
| WO-1993011144-A1 | NEW METHOD OF PREPARING 2-FLUOROPURINE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-06-10 | — | — | WO | disclosed |
| US-4997926-A | Viricides | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0355135-A4 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES. | SCRIPPS CLINIC RES (US) | 1990-04-09 | — | — | EP | disclosed |
| EP-0355135-A1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1990-02-28 | — | — | EP | disclosed |
| WO-1989004662-A1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1989-06-01 | — | — | WO | disclosed |