Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | VDR | P11473 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783952 | 0.92 | ALDH1A1 (0.59) | ALDH1A1LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL11589505 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL1787080 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL1788004 | 0.78 | LMNA (0.53) | ALDH1A1LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL1786188 | 0.74 | PIK3CA (0.52) | ALDH1A1LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL1789550 | 0.74 | LMNA (0.51) | ALDH1A1LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL1787659 | 0.74 | LMNA (0.51) | ALDH1A1LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL1786763 | 0.74 | LMNA (0.51) | ALDH1A1LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL5433438 | 0.72 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDHSD17B10KDM4E | |
| SCHEMBL5433443 | 0.72 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205576-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009047558-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2009-04-16 | — | — | WO | disclosed |