SCHEMBL3655359

SCHEMBL3655359

CC#CCCOc1cccc(NC)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.49
THRB P10828 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SYK P43405 2/20 0.37
MAPK1 P28482 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
DRD3 P35462 1/20 0.36
FAAH O00519 1/20 0.36
MAOB P27338 1/20 0.36
LMNA P02545 1/20 0.35
HTR1D P28221 1/20 0.35
HTR1B P28222 1/20 0.35
F2 P00734 1/20 0.35
ROCK2 O75116 1/20 0.35
PRKACA P17612 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3662194 0.92 APP (0.48) APPTHRBMEN1KMT2ASYK
SCHEMBL3659405 0.91 APP (0.47) APPTHRBMEN1KMT2ASYK
SCHEMBL3662742 0.90 APP (0.46) APPTHRBTSHRFAAHMAOB
SCHEMBL3661397 0.86 APP (0.48) APPTHRBMEN1KMT2AMAPK1
SCHEMBL3655639 0.86 APP (0.48) APPTHRBMEN1KMT2AMAPK1
SCHEMBL3659653 0.84 APP (0.51) APPMEN1KMT2ASYKMAPK1
SCHEMBL3658408 0.84 THRB (0.48) APPTHRBMEN1KMT2AMAPK1
SCHEMBL3660250 0.83 APP (0.50) APPTHRBMEN1KMT2AMAPK1
SCHEMBL3659980 0.79 APP (0.47) APPTHRBKMT2AMAPK1TSHR
SCHEMBL3658934 0.79 APP (0.47) APPTHRBMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 APP 2380/4885THRB 2450/4885MEN1 786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.