SCHEMBL3661397

SCHEMBL3661397

CCC#CCCOc1cccc(NC)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.48
THRB P10828 1/20 0.41
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
FAAH O00519 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
NR1H4 Q96RI1 3/20 0.36
TSHR P16473 1/20 0.36
DRD2 P14416 1/20 0.35
DRD4 P21917 1/20 0.35
DRD3 P35462 1/20 0.35
MAOB P27338 1/20 0.35
CASP3 P42574 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3658934 0.93 APP (0.47) APPTHRBHTTHSD17B10FAAH
SCHEMBL3662533 0.91 APP (0.46) APPTHRBHTTHSD17B10FAAH
SCHEMBL3655639 0.91 APP (0.48) APPTHRBHTTHSD17B10FAAH
SCHEMBL3658408 0.88 THRB (0.48) APPTHRBFAAHKMT2AMEN1
SCHEMBL3655359 0.86 APP (0.49) APPTHRBHTTHSD17B10FAAH
SCHEMBL3663859 0.84 APP (0.50) APPTHRBHTTHSD17B10KMT2A
SCHEMBL3659980 0.84 APP (0.47) APPTHRBHTTHSD17B10FAAH
SCHEMBL3660250 0.81 APP (0.50) APPTHRBHTTHSD17B10FAAH
SCHEMBL5609143 0.80 APP (0.55) APPTHRBHTTFAAHKMT2A
SCHEMBL13169873 0.79 THRB (0.60) APPTHRBFAAHKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 APP 2380/4885THRB 2450/4885HTT 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.