Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL8672611 | 0.94 | TDP1 (0.47) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Propane SCHEMBL8522373 | 0.88 | TDP1 (0.43) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL18241084 | 0.84 | TDP1 (0.39) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL17414853 | 0.80 | TDP1 (0.36) | TDP1CYP3A4ESR1ESR2 | |
| SCHEMBL2733013 | 0.80 | CYP3A4 (0.36) | TDP1CYP3A4ESR1ESR2LMNA | |
| Hydrochloric Acid SCHEMBL19723221 | 0.78 | CYP3A4 (0.35) | TDP1CYP3A4ESR1ESR2 | |
| SCHEMBL987669 | 0.74 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL2387556 | 0.71 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Benzene SCHEMBL6890099 | 0.69 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL101 | 0.69 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907381-B | Photosensitizer with thiadiazolo [3,4-g ] quinoxaline structure with distorted molecular framework, preparation and application thereof | 中国科学院理化技术研究所 | 2023-09-29 | — | — | CN | claimed |
| CN-110028392-B | Method for isomerizing and synthesizing isopropenal by using methylbutynol | 山东新和成药业有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-110028392-A | A kind of method of methyl butynol iso-synthesis isoamyl olefine aldehydr | 山东新和成药业有限公司 | 2019-07-19 | — | — | CN | claimed |
| CN-107008501-A | A kind of hydrophilic mesoporous silicon nanosphere of the bimetallic support type containing palladium and chiral ruthenium complex and preparation method thereof | 上海师范大学 | 2017-08-04 | — | — | CN | claimed |
| CN-103962152-B | A kind of Ru-Pd bimetallic load type chiral catalyst and preparation technology thereof | 上海师范大学 | 2016-07-06 | — | — | CN | claimed |
| CN-104941686-A | Egg shell-like structure palladium ruthenium bimetallic functionalization mesoporous nanometer catalyst and preparation method thereof | UNIV SHANGHAI | 2015-09-30 | — | — | CN | claimed |
| CN-103962152-A | Ru-Pd bi-metal loading chiral catalyst and preparation technology thereof | UNIV SHANGHAI | 2014-08-06 | — | — | CN | claimed |
| EP-3833668-B1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-4436956-A1 | LIGANDS SPECIFICALLY TARGETING VESICULAR GLUTAMATE TRANSPORTERS FOR SUPER-RESOLUTION IMAGING | Sorbonne Université (FR) | 2024-10-02 | — | — | EP | disclosed |
| CN-113348165-B | 1,2, 4-Triazin-3 (2H) -one compounds for the treatment of hyperproliferative diseases | 拜耳股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| US-11993602-B2 | PRMT5 inhibitors | MERCK SHARP & DOHME LLC (US) | 2024-05-28 | — | — | US | disclosed |
| CN-117295744-A | Method for producing benzoxazole derivative having bicyclic piperazine ring or salt thereof, and method for producing raw material therefor | 明治制果药业株式会社 | 2023-12-26 | — | — | CN | disclosed |
| CN-116854630-A | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-2203499-A1 | PROCESS FOR PREPARATION OF CONDUCTING POLYMERS | BASF SE (DE) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009053468-A1 | PROCESS FOR PREPARATION OF CONDUCTING POLYMERS | BASF SE (DE) | 2009-04-30 | — | — | WO | disclosed |
| CN-1953982-A | 4-substituted 1,5-dihydro-pyrido(3,2-b)indol-2-ones | TIBOTEC PHARM LTD (IE) | 2007-04-25 | — | — | CN | disclosed |
| WO-2005066243-A1 | WATER-SOLUBLE POLYTHIOPHENE POLYMERS | RIEKE METALS, INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| US-5964919-A | STABILIZING THE ACTIVE ZINC BY SUSPENDING IN A CONTAINER WITH AN SOLVENT SELECT FROM ETHER, HYDROCARBON, AROMATIC HYDROCARABON OR APROTIC SOLVENT UNDER INERT GAS, SEALING THE CONTAINER | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1999-10-12 | — | — | US | disclosed |
| WO-1993015086-A1 | HIGHLY REACTIVE FORMS OF ZINC AND REAGENTS THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-08-05 | — | — | WO | disclosed |
| WO-1993003071-A1 | PREPARATION OF FUNCTIONALIZED POLYMERS UTILIZING A REACTIVE FORM OF CALCIUM | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11993602-B2 | PRMT5 inhibitors | PRMT5, PRMT1, PRMT6 | TDP1 1201/4885CYP3A4 2057/4885ESR1 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.