SCHEMBL3655846

SCHEMBL3655846

COc1ccc(CC(Cl)(Cl)Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ALDH1A1 P00352 4/20 0.48
ALOX15 P16050 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
CMA1 P23946 1/20 0.48
AGXT P21549 2/20 0.48
LTA4H P09960 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
TDP1 Q9NUW8 3/20 0.47
TSHR P16473 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP3A4 P08684 2/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596580 0.86 IDO1 (0.52) IDO1CA12CA1CA2CA7
SCHEMBL16424752 0.81 IDO1 (0.56) IDO1CA12CA1CA2CA7
SCHEMBL3122385 0.79 CALM1 (0.47) IDO1CA12CA1CA2CA7
SCHEMBL2875596 0.79 IDO1 (0.45) IDO1CA12CA1CA2CA7
SCHEMBL73472 0.79 IDO1 (0.54) IDO1CA12CA1CA2CA7
SCHEMBL3719895 0.77 IDO1 (0.52) IDO1CA12CA1CA2CA7
SCHEMBL30457023 0.77 IDO1 (0.52) IDO1CA12CA1CA2CA7
SCHEMBL330750 0.77 IDO1 (0.58) IDO1CA12CA1CA2CA7
SCHEMBL574696 0.77 LTA4H (0.53) IDO1ALDH1A1ALOX15LTA4HTSHR
SCHEMBL9341171 0.77 LTA4H (0.53) IDO1LTA4HSMN1; SMN2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0799159-A1 DECHLORINATION OF TCE WITH PALLADIZED IRON Research Corporation Technologies, Inc (US) 1997-10-08 EP claimed
WO-1996020137-A1 DECHLORINATION OF TCE WITH PALLADIZED IRON RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1996-07-04 WO claimed
US-5205067-A Device and method for treating mausoleums against phorid fly infestation THOMAS MATTHEW J (US) 1993-04-27 US claimed
US-5148627-A Method for treating mausoleums against phorid fly infestation THOMAS MATTHEW J (US) 1992-09-22 US claimed
US-4566996-A Process for preparing azetidinone derivatives Otsuke Kagaku Yakuhin Kabushiki Kaisha (JP) 1986-01-28 US claimed
CN-112368336-A Resin composition and cured film thereof 东丽株式会社 2021-02-12 CN disclosed
CN-103736240-B Fire extinguishing composition containing saturated hydrocarbon compound and derivatives thereof 湖北及安盾消防科技有限公司 2020-10-13 CN disclosed
EP-1942150-B1 SILOXANE RESIN COMPOSITION AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES (JP) 2018-08-22 EP disclosed
CN-101395534-B Thermosetting composition for protective film, cured product, and liquid crystal display device MITSUBISHI CHEM CORP 2013-06-19 CN disclosed
CN-103000723-A Solar cell MOTECH IND INC 2013-03-27 CN disclosed
CN-101395535-B Thermosetting composition for protective film, cured product, and liquid crystal display device MITSUBISHI CHEM CORP 2013-03-20 CN disclosed
CN-102591150-A Thermosetting composition for protective film, cured product, and liquid crystal display device MITSUBISHI CHEM CORP 2012-07-18 CN disclosed
US-4713452-A Process for preparation of azetidinone derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1987-12-15 US disclosed
EP-0117875-B1 PROCESS FOR PREPARING AZETIDINONE DERIVATIVES OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1987-07-22 EP disclosed
EP-0214600-A2 Cephalosporin derivatives Otsuka Kagaku Kabushiki Kaisha (JP) 1987-03-18 EP disclosed
US-4622178-A CEPHALOSPORIN INTERMEDIATES OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1986-11-11 US disclosed
EP-0190996-A2 Crosslinked, porous polymers for controlled delivery of agricultural ingredients CIBA-GEIGY AG (CH) 1986-08-13 EP disclosed
US-4599151-A ELECTROLYTIC OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1986-07-08 US disclosed
US-4566996-A Process for preparing azetidinone derivatives Otsuke Kagaku Yakuhin Kabushiki Kaisha (JP) 1986-01-28 US disclosed
EP-0114729-A1 Process for preparing azetidinone derivatives OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1984-08-01 EP disclosed