Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644389 | 0.84 | HPGD (0.41) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL1643388 | 0.81 | HPGD (0.40) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL17534865 | 0.81 | HPGD (0.38) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL3652116 | 0.79 | ALDH1A1 (0.38) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL1942298 | 0.78 | ALDH1A1 (0.36) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL3654597 | 0.78 | ALDH1A1 (0.36) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL1608876 | 0.76 | HPGD (0.63) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL31034517 | 0.75 | FTO (0.39) | HPGDALDH1A1POLBSMAD3MEN1 | |
| Hydrochloric Acid SCHEMBL25316086 | 0.75 | HPGD (0.62) | HPGDALDH1A1BRCA1HSD17B10CYP2C9 | |
| SCHEMBL2859711 | 0.74 | FTO (0.42) | HPGDALDH1A1POLBSMAD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230120665-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | LIFE TECHNOLOGIES CORP (US) | 2023-04-20 | — | — | US | disclosed |
| US-20190242912-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation | 2019-08-08 | — | — | US | disclosed |
| US-20170067918-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation | 2017-03-09 | — | — | US | disclosed |
| US-9476892-B2 | Composition and method for measuring thallium influx and efflux | Life Technologies Corporation (US) | 2016-10-25 | — | — | US | disclosed |
| US-20150104823-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation | 2015-04-16 | — | — | US | disclosed |
| EP-2201367-B1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | LIFE TECHNOLOGIES CORP (US) | 2013-03-20 | — | — | EP | disclosed |
| EP-2562543-A1 | Composition and method for measuring thallium influx and efflux | Life Technologies Corporation (US) | 2013-02-27 | — | — | EP | disclosed |
| US-20100279314-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation | 2010-11-04 | — | — | US | disclosed |
| EP-2201367-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | Life Technologies Corporation (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009052183-A1 | COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX | INVITROGEN CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |
| US-6229055-B1 | SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES | MOLECULAR PROBES, INC. | 2001-05-08 | — | — | US | disclosed |
| US-6162931-A | Fluorinated xanthene derivatives | MOLECULAR PROBES, INC. (US) | 2000-12-19 | — | — | US | disclosed |