Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193031 | 0.80 | KMT2A (0.65) | KMT2ASRD5A2ALDH1A1L3MBTL1CA1 | |
| SCHEMBL28744386 | 0.78 | KMT2A (0.67) | KMT2ASRD5A2ALDH1A1CA1CA2 | |
| SCHEMBL75998 | 0.78 | ALDH1A1 (0.39) | KMT2AALDH1A1TSHRPKMCA4 | |
| SCHEMBL175074 | 0.78 | TSHR (0.44) | KMT2ASRD5A2ALDH1A1L3MBTL1CA1 | |
| SCHEMBL11314174 | 0.77 | KMT2A (0.56) | KMT2ASRD5A2ALDH1A1L3MBTL1CA1 | |
| SCHEMBL24086152 | 0.77 | HTT (0.63) | ALDH1A1L3MBTL1TSHRTP53HTT | |
| Hydrochloric Acid SCHEMBL11310398 | 0.76 | KMT2A (0.54) | KMT2ASRD5A2ALDH1A1L3MBTL1CA1 | |
| SCHEMBL9268887 | 0.76 | KMT2A (0.50) | KMT2ASRD5A2ALDH1A1L3MBTL1CA1 | |
| SCHEMBL8634740 | 0.75 | KMT2A (0.49) | KMT2ASRD5A2ALDH1A1L3MBTL1CA1 | |
| SCHEMBL10867743 | 0.75 | KMT2A (0.74) | KMT2ASRD5A2ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041234-B2 | Methods for synthesis of liquid crystals | SOUTHWEST RESEARCH INSTITUTE (US) | 2006-05-09 | — | — | US | claimed |
| EP-1572716-A4 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | SOUTHWEST RES INST (US) | 2005-09-14 | — | — | EP | claimed |
| EP-1572716-A2 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | Southwest Research Institute (US) | 2005-09-14 | — | — | EP | claimed |
| US-20030055280-A1 | Methods for synthesis of liquid crystals | SOUTHWEST RESEARCH INSTITUTE | 2003-03-20 | — | — | US | claimed |
| WO-2002066493-A2 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | SOUTHWEST RESEARCH INSTITUTE (US) | 2002-08-29 | — | — | WO | claimed |
| EP-1366133-B1 | NOVEL METHODS AND BLENDS FOR CONTROLLING REHOLOGY AND TRANSITION TEMPERATURE OF LIQUID CRYSTALS | SOUTHWEST RES INST (US) | 2010-03-24 | — | — | EP | disclosed |
| EP-1370512-B1 | NOVEL MESOGENS | SOUTHWEST RES INST (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-1412447-B1 | NOVEL MESOGENS AND METHODS FOR THEIR SYNTHESIS AND USE | SOUTHWEST RES INST (US) | 2008-09-10 | — | — | EP | disclosed |
| US-7238831-B2 | Mesogens | SOUTHWEST RESEARCH INSTITUTE (US) | 2007-07-03 | — | — | US | disclosed |
| EP-1572716-B1 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | SOUTHWEST RES INST (US) | 2006-09-27 | — | — | EP | disclosed |
| US-7108801-B2 | Methods and blends for controlling rheology and transition temperature of liquid crystals | SOUTHWEST REASEARCH INSTITUTE (US) | 2006-09-19 | — | — | US | disclosed |
| US-7098359-B2 | Mesogens and methods for their synthesis and use | SOUTHWEST RESEARCH INSTITUTE (US) | 2006-08-29 | — | — | US | disclosed |
| US-20030055280-A1 | Methods for synthesis of liquid crystals | SOUTHWEST RESEARCH INSTITUTE | 2003-03-20 | — | — | US | disclosed |
| US-20030036609-A1 | Novel methods and blends for controlling rheology and transition temperature of liquid crystals | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-02-20 | — | — | US | disclosed |
| WO-2003006570-A2 | NOVEL MESOGENS AND METHODS FOR THEIR SYNTHESIS AND USE | SOUTHWEST RESEARCH INSTITUTE (US) | 2003-01-23 | — | — | WO | disclosed |
| US-20020177727-A1 | Novel mesogens | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-28 | — | — | US | disclosed |
| WO-2002066493-A2 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | SOUTHWEST RESEARCH INSTITUTE (US) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002059553-A2 | NOVEL METHODS AND BLENDS FOR CONTROLLING REHOLOGY AND TRANSITION TEMPERATURE OF LIQUID CRYSTALS | SOUTHWEST RESEARCH INSTITUTE (US) | 2002-08-01 | — | — | WO | disclosed |
| WO-2002059227-A2 | NOVEL MESOGENS | SOUTHWEST RESEARCH INSTITUTE (US) | 2002-08-01 | — | — | WO | disclosed |
| US-4661576-A | LIQUID CRYSTALS | THOMSON-CSF (FR) | 1987-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055280-A1 | Methods for synthesis of liquid crystals | WEE1, WEE2, NUP188 | KMT2A 4008/4885SRD5A2 2864/4885ALDH1A1 4432/4885 |
| US-20020177727-A1 | Novel mesogens | AREG, MAG, GMFG | KMT2A 2256/4885SRD5A2 2367/4885ALDH1A1 3700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.