Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364634 | 0.89 | PROKR1 (0.35) | PROKR1SMARCA2SMARCA4SORT1RAB9A | |
| SCHEMBL363084 | 0.88 | SORT1 (0.34) | PROKR1SMARCA2SMARCA4SORT1KDM4E | |
| SCHEMBL364587 | 0.88 | SORT1 (0.34) | PROKR1SMARCA2SMARCA4SORT1KDM4E | |
| SCHEMBL362712 | 0.88 | SORT1 (0.34) | PROKR1SMARCA2SMARCA4SORT1KDM4E | |
| SCHEMBL363061 | 0.86 | KCNN4 (0.34) | SORT1KDM4EKDM5AKDM4CKDM5B | |
| SCHEMBL363109 | 0.86 | CASR (0.34) | CDC7EEF2KPLK4AURKAPDPK1 | |
| SCHEMBL363457 | 0.85 | CCR9 (0.38) | FLT4PROKR1CCR9 | |
| SCHEMBL364004 | 0.85 | MAPT (0.41) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL364575 | 0.83 | KCNN4 (0.40) | SMARCA2SMARCA4SORT1FTOKDM4E | |
| SCHEMBL364421 | 0.81 | PROKR1 (0.38) | MAPKAPK2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |