Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363321 | 0.89 | TLR9 (0.36) | PROKR1IDO1TLR9TLR7TLR8 | |
| SCHEMBL363070 | 0.85 | ALDH1A1 (0.41) | PROKR1IDO1TLR7TLR8 | |
| SCHEMBL364634 | 0.82 | PROKR1 (0.35) | PROKR1IDO1 | |
| SCHEMBL362712 | 0.81 | SORT1 (0.34) | PROKR1IDO1 | |
| SCHEMBL363084 | 0.81 | SORT1 (0.34) | PROKR1IDO1 | |
| SCHEMBL364587 | 0.81 | SORT1 (0.34) | PROKR1IDO1 | |
| SCHEMBL365757 | 0.81 | CDC7 (0.35) | PROKR1MAPKAPK2 | |
| SCHEMBL363150 | 0.80 | TLR9 (0.36) | PROKR1IDO1TLR9TLR7TLR8 | |
| SCHEMBL363457 | 0.78 | CCR9 (0.38) | PROKR1 | |
| SCHEMBL364745 | 0.77 | MAPK1 (0.34) | PROKR1TLR9TLR7TLR8P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |