Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | STAT6 | P42226 | 2/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GALR3 | O60755 | 1/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ADK | P55263 | 7/20 | 0.56 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658127 | 1.00 | HIF1A (1.00) | HIF1ATP53STAT6PAX8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2386489 | 0.99 | HIF1A (0.98) | HIF1ATP53STAT6PAX8ALDH1A1 | |
| SCHEMBL26031534 | 0.89 | HIF1A (0.80) | HIF1ATP53STAT6PAX8ALDH1A1 | |
| SCHEMBL2788440 | 0.87 | HIF1A (0.77) | HIF1ATP53STAT6PAX8ALDH1A1 | |
| SCHEMBL2788446 | 0.87 | HIF1A (0.77) | HIF1ATP53STAT6PAX8ALDH1A1 | |
| SCHEMBL25025607 | 0.87 | NPC1 (0.77) | HIF1ATP53STAT6PAX8ALDH1A1 | |
| SCHEMBL13021233 | 0.86 | HIF1A (0.75) | HIF1ATP53STAT6PAX8ALDH1A1 | |
| SCHEMBL2784937 | 0.86 | HIF1A (0.75) | HIF1ATP53STAT6PAX8ALDH1A1 | |
| SCHEMBL2784929 | 0.86 | HIF1A (0.75) | HIF1ATP53STAT6PAX8ALDH1A1 | |
| SCHEMBL13021287 | 0.86 | TP53 (0.75) | HIF1ATP53STAT6PAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2214670-A2 | COMPOUNDS FOR TREATING ABNORMAL CELLULAR PROLIFERATION | Taiga Biotechnologies, Inc. (US) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009059304-A2 | COMPOUNDS FOR TREATING ABNORMAL CELLULAR PROLIFERATION | TAIGA BIOTECHNOLOGIES, INC. (US) | 2009-05-07 | — | — | WO | disclosed |