Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.75 |
| ▸ | TP53 | P04637 | 3/20 | 0.75 |
| ▸ | STAT6 | P42226 | 2/20 | 0.75 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.68 |
| ▸ | ADK | P55263 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784929 | 1.00 | HIF1A (0.75) | HIF1ATP53STAT6PAX8ADK | |
| SCHEMBL2784937 | 1.00 | HIF1A (0.75) | HIF1ATP53STAT6PAX8ADK | |
| SCHEMBL13021323 | 0.87 | HIF1A (0.57) | HIF1ATP53STAT6PAX8 | |
| SCHEMBL2788440 | 0.87 | HIF1A (0.77) | HIF1ATP53STAT6PAX8ADK | |
| SCHEMBL2788446 | 0.87 | HIF1A (0.77) | HIF1ATP53STAT6PAX8ADK | |
| SCHEMBL3658127 | 0.86 | HIF1A (1.00) | HIF1ATP53STAT6PAX8ADK | |
| SCHEMBL3658125 | 0.86 | HIF1A (1.00) | HIF1ATP53STAT6PAX8ADK | |
| Hydrochloric Acid SCHEMBL2386489 | 0.85 | HIF1A (0.98) | HIF1ATP53STAT6PAX8ADK | |
| SCHEMBL2786328 | 0.85 | HIF1A (0.74) | HIF1ATP53STAT6PAX8ADK | |
| SCHEMBL2786320 | 0.85 | HIF1A (0.74) | HIF1ATP53STAT6PAX8ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297079-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | CHIMERIX, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100297079-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | CHIMERIX, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| WO-2010135520-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | CHIMERIX, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297079-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | HAVCR2, EIF2AK2, OAT | HIF1A 247/4885TP53 2531/4885STAT6 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.