Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.75 |
| ▸ | STAT6 | P42226 | 2/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GALR3 | O60755 | 1/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | ADK | P55263 | 10/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25025607 | 0.88 | NPC1 (0.77) | TP53STAT6HIF1AALDH1A1HTT | |
| SCHEMBL3658125 | 0.86 | HIF1A (1.00) | TP53STAT6HIF1AALDH1A1HTT | |
| SCHEMBL3658127 | 0.86 | HIF1A (1.00) | TP53STAT6HIF1AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL2386489 | 0.85 | HIF1A (0.98) | TP53STAT6HIF1AALDH1A1HTT | |
| SCHEMBL2788446 | 0.83 | HIF1A (0.77) | TP53STAT6HIF1AALDH1A1HTT | |
| SCHEMBL2788440 | 0.83 | HIF1A (0.77) | TP53STAT6HIF1AALDH1A1HTT | |
| SCHEMBL13021233 | 0.82 | HIF1A (0.75) | TP53STAT6HIF1AALDH1A1HTT | |
| SCHEMBL2784937 | 0.82 | HIF1A (0.75) | TP53STAT6HIF1AALDH1A1HTT | |
| SCHEMBL2784929 | 0.82 | HIF1A (0.75) | TP53STAT6HIF1AALDH1A1HTT | |
| SCHEMBL17816346 | 0.82 | ADK (0.61) | TP53STAT6HIF1AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297079-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | CHIMERIX, INC. (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297079-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | HAVCR2, EIF2AK2, OAT | TP53 2531/4885STAT6 1884/4885HIF1A 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.