SCHEMBL3658368

SCHEMBL3658368

CN1C(=O)C(CCO)N(C)C1=O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
BRD4 O60885 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ADRA2C P18825 1/20 0.32
CAPN1 P07384 1/20 0.32
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28235177 0.88 KDM4E (0.35) KDM4EALDH1A1MAPTBRD4MEN1
SCHEMBL503017 0.83 KDM4E (0.38) KDM4EALDH1A1MAPTBRD4MEN1
SCHEMBL27696934 0.81 GAA (0.36) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL11600812 0.79 NPSR1 (0.46) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL28236238 0.79 KDM4E (0.37) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL17830321 0.79 ALDH1A1 (0.44) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL11550750 0.76 KDM4E (0.33) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL19923589 0.76 KDM4E (0.36) KDM4EALDH1A1MAPTBRD4MEN1
SCHEMBL25407083 0.74 KDM4E (0.35) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL31694806 0.73 KDM4E (0.48) KDM4EALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117425708-A Coating composition and coating film 日涂企业服务有限公司 2024-01-19 CN disclosed
CN-115135734-A Aqueous coating composition and method for forming multilayer coating film 日涂汽车涂料有限公司 2022-09-30 CN disclosed
CN-112313297-B Aqueous coating composition and method for producing aqueous coating composition 日涂汽车涂料有限公司 2022-05-13 CN disclosed
CN-112313297-A Aqueous coating composition and method for producing aqueous coating composition 日涂汽车涂料有限公司 2021-02-02 CN disclosed
US-20200140702-A1 CURING AGENT FOR COATING COMPOSITION FOR FORMING SELF-RESTORABLE LAYER, COATING COMPOSITION HAVING THE SAME AND METHOD FOR COATING AUTOMOBILE EXTERIOR USING THE SAME NOROO BEE CHEMICAL CO., LTD. (KR) 2020-05-07 US disclosed
CN-105492001-B Article with reactive metal bonded on surface and application method 托米酷跑知识产权股份有限公司 2019-12-24 CN disclosed
CN-105254843-B Polyisocyantates composition, blocked polyisocyanates composition and their manufacturing method 旭化成株式会社 2019-08-06 CN disclosed
CN-107108830-A Polyisocyantates composition and its manufacture method, blocked polyisocyanates composition and its manufacture method, resin combination and solidfied material 旭化成株式会社 2017-08-29 CN disclosed
EP-2235084-A1 POLYURETHANES WITH NONIONIC HYDROPHILIC TERMINATING GROUPS AND AQUEOUS DISPERSIONS THEREOF E. I. du Pont de Nemours and Company (US) 2010-10-06 EP disclosed
WO-2009076379-A1 POLYURETHANES WITH NONIONIC HYDROPHILIC TERMINATING GROUPS AND AQUEOUS DISPERSIONS THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-18 WO disclosed
US-5167941-A Sulfur dioxide; cationic polyelectrolyte stabilizers THE DOW CHEMICAL COMPANY (US) 1992-12-01 US disclosed
US-5114630-A Highly filled elastomeric binder THE UNITED OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1992-05-19 US disclosed
EP-0283172-B1 LOAD-BEARING ARTICLE HAVING SURFACE LUBRICITY ICI AMERICAS INC. (US) 1992-04-22 EP disclosed
US-5100907-A Surfactant and biocide preservatives LONZA, INC. (US) 1992-03-31 US disclosed
EP-0283172-A1 Load-bearing article having surface lubricity ICI AMERICAS INC. (US) 1988-09-21 EP disclosed
US-4766194-A ISOCYANATE-REACTIVE LUBRICANT INCORPORATED INTO POLYURETHANE MOLDING ICI AMERICAS INC. (US) 1988-08-23 US disclosed
US-4317894-A Low temperature cure coating compositions PPG INDUSTRIES, INC. (US) 1982-03-02 US disclosed
US-4204010-A Radiation curable, ethylenically unsaturated thixotropic agent and method of preparation W. R. GRACE & CO. (US) 1980-05-20 US disclosed
US-4134873-A BIURET OF HEXAMETHYLENE DIISOCYANATE, POLYESTER OF DI-(2-HYDROXYETHYL)DIMETHYLHYDANTOIN, TRIMETHYLOLPROPANE, DIMETHYL TEREPHTHALATE, ADIPIC ACID AND HEXAMETHYLENEDIOL DESOTO, INC. (US) 1979-01-16 US disclosed
US-3984606-A Curable polyene-polythiol hydantoin coating compositions W. R. GRACE & CO. (US) 1976-10-05 US disclosed