SCHEMBL503017

SCHEMBL503017

CN1C(=O)C(CO)N(C)C1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 5/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
ADRA2C P18825 1/20 0.35
CAPN1 P07384 1/20 0.33
HIF1A Q16665 1/20 0.33
BRD4 O60885 1/20 0.32
MAPK1 P28482 1/20 0.32
ADORA3 P0DMS8 2/20 0.31
ADORA2A P29274 2/20 0.31
ADORA1 P30542 1/20 0.31
HSD17B10 Q99714 2/20 0.31
KDM4A O75164 2/20 0.31
KDM4C Q9H3R0 2/20 0.31
TP53 P04637 1/20 0.31
GLA P06280 1/20 0.31
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dioxane SCHEMBL9486523 0.89 KDM4E (0.36) KDM4EALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL10501254 0.86 KDM4E (0.35) KDM4EALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL3658368 0.83 KDM4E (0.37) KDM4EALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL25937459 0.80 CAPN1 (0.47) KDM4EALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL28235177 0.79 KDM4E (0.35) KDM4EALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL9193310 0.79 CRBN (0.33) KDM4EL3MBTL1KMT2AMEN1
SCHEMBL19923589 0.79 KDM4E (0.36) KDM4EALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL4778463 0.78 HDAC6 (0.35) L3MBTL1ADRA2CCAPN1BRD4MAPK1
SCHEMBL25407083 0.77 KDM4E (0.35) KDM4EALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL31694806 0.77 KDM4E (0.48) KDM4EALDH1A1MAPTL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1545210-B1 STABLE, LOW FREE FORMALDEHYDE, SYNERGISTIC ANTIMICROBIAL COMPOSITIONS OF ALDEHYDE DONORS AND DEHYDROACETIC ACID LONZA AG (US) 2007-01-24 EP claimed
EP-1545210-A1 STABLE, LOW FREE FORMALDEHYDE, SYNERGISTIC ANTIMICROBIAL COMPOSITIONS OF ALDEHYDE DONORS AND DEHYDROACETIC ACID LONZA, INC. (US) 2005-06-29 EP claimed
US-20050136504-A1 Method of measurement of protease and thin membranes used for said method FUJI PHOTO FILM CO., LTD. 2005-06-23 US claimed
US-20040102501-A1 Stable, low free formaldehyde, synergistic antimicrobial compositions of aldehyde donors and dehydroacetic acid LUTZ PATRICK JAY (US) 2004-05-27 US claimed
WO-2004017736-A1 STABLE, LOW FREE FORMALDEHYDE, SYNERGISTIC ANTIMICROBIAL COMPOSITIONS OF ALDEHYDE DONORS AND DEHYDROACETIC ACID LONZA, INC. (US) 2004-03-04 WO claimed
US-6681691-B2 Screen printing stencil production AUTOTYPE INTERNATIONAL LIMITED (GB) 2004-01-27 US claimed
EP-1022950-B1 STABILISED MIXTURES OF AN IODOPROPARGYL COMPOUND AND A FORMALDEHYDE DONOR LONZA AG (US) 2003-08-20 EP claimed
US-6582627-B1 Aqueous liquid, broad-spectrum, low free-formaldehyde synergistic preservative mixtures of an iodopropynyl compound and a formaldehyde donor LONZA INC. 2003-06-24 US claimed
US-6539856-B2 Method of screen printing stencil production AUTOTYPE INTERNATIONAL LIMITED (GB) 2003-04-01 US claimed
EP-0909642-B1 Screen printing stencil production AUTOTYPE INTERNAT LTD (GB) 2003-03-12 EP claimed
EP-0996545-A1 SCREEN PRINTING STENCIL PRODUCTION AUTOTYPE INTERNATIONAL LIMITED (GB) 2000-05-03 EP claimed
EP-0936064-A1 Screen printing stencil production AUTOTYPE INTERNATIONAL LIMITED (GB) 1999-08-18 EP claimed
EP-0909642-A1 Screen printing stencil production AUTOTYPE INTERNATIONAL LIMITED (GB) 1999-04-21 EP claimed
WO-1999002344-A1 SCREEN PRINTING STENCIL PRODUCTION AUTOTYPE INTERNATIONAL LIMITED (GB) 1999-01-21 WO claimed
EP-0571903-B1 A method for preparing low free formaldehyde methylol-hydantoins and compositions thereof LONZA AG (US) 1996-08-28 EP claimed
EP-0571904-B1 Process for preparing methylolhydantoins LONZA AG (US) 1995-10-25 EP claimed
US-5405862-A Microbiocides LONZA INC. (US) 1995-04-11 US claimed
EP-0571903-A1 A method for preparing low free formaldehyde methylol-hydantoins and compositions thereof LONZA INC. (US) 1993-12-01 EP claimed
EP-0571904-A1 Process for preparing methylolhydantoins LONZA INC. (US) 1993-12-01 EP claimed
US-5252744-A Liquid based methods for the production of solid, anhydrous methylolhydantoins LONZA INC. (US) 1993-10-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102501-A1 Stable, low free formaldehyde, synergistic antimicrobial compositions of aldehyde donors and dehydroacetic acid HAO2, HDHD5, DDC KDM4E 2389/4885ALDH1A1 117/4885MAPT 3477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.