Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661317 | 0.89 | HRH3 (0.43) | JAK3HRH3 | |
| SCHEMBL3657582 | 0.87 | HRH3 (0.41) | JAK3HRH3 | |
| Trifluoroacetic Acid SCHEMBL3660055 | 0.84 | HRH3 (0.39) | JAK3HRH3 | |
| SCHEMBL3662226 | 0.83 | EPHX1 (0.49) | — | |
| SCHEMBL3657525 | 0.82 | KMT2A (0.49) | JAK3 | |
| Trifluoroacetic Acid SCHEMBL3660920 | 0.81 | HRH3 (0.38) | JAK3HRH3 | |
| Trifluoroacetic Acid SCHEMBL3654963 | 0.80 | — | — | |
| SCHEMBL3650418 | 0.79 | EPHX2 (0.48) | — | |
| SCHEMBL3657680 | 0.79 | RAB9A (0.51) | — | |
| SCHEMBL3656607 | 0.78 | KMT2A (0.47) | JAK3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215058-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE UREAS AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-11 | — | — | EP | claimed |
| WO-2009052068-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE UREAS AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | claimed |
| EP-2215058-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE UREAS AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009052068-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE UREAS AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |