SCHEMBL3659247

SCHEMBL3659247

COc1cc(F)ccc1/C(=C/c1ccccc1C)CCl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.39
LMNA P02545 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 2/20 0.39
PLIN1 O60240 1/20 0.39
POLB P06746 1/20 0.39
PLIN5 Q00G26 1/20 0.39
ABHD5 Q8WTS1 1/20 0.39
ALOX5 P09917 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
NR3C1 P04150 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NFE2L2 Q16236 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HTT P42858 1/20 0.35
PAX8 Q06710 1/20 0.35
RELA Q04206 1/20 0.35
NPC1 O15118 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3821269 1.00 AR (0.39) ARLMNAMEN1KMT2AMAPT
SCHEMBL3664086 0.89 NFE2L2 (0.46) ARLMNAMEN1KMT2AMAPT
SCHEMBL3772509 0.89 NFE2L2 (0.46) ARLMNAMEN1KMT2AMAPT
SCHEMBL3662315 0.88 ABCG2 (0.44) ARLMNAMEN1KMT2AMAPT
SCHEMBL3662316 0.88 ABCG2 (0.44) ARLMNAMEN1KMT2AMAPT
SCHEMBL3778957 0.82 MEN1 (0.38) ARMEN1KMT2AMAPTPTGS1
SCHEMBL3656538 0.82 MEN1 (0.38) ARMEN1KMT2AMAPTPTGS1
SCHEMBL3771354 0.80 CPS1 (0.39) LMNAMEN1KMT2AMAPTNFE2L2
SCHEMBL3660866 0.80 CPS1 (0.39) LMNAMEN1KMT2AMAPTNFE2L2
SCHEMBL11707546 0.77 KMT2A (0.50) ARLMNAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100317515-A1 Azolylmethyloxiranes, use Thereof and Agents Containing the Same BASF SE (DE) 2010-12-16 US disclosed
EP-2234488-A2 AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME BASF SE (DE) 2010-10-06 EP disclosed
WO-2009077443-A2 AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME BASF SE (DE) 2009-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317515-A1 Azolylmethyloxiranes, use Thereof and Agents Containing the Same XDH, NOX5, TET1 AR 3658/4885LMNA 4209/4885MEN1 1724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.