Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659269 | 1.00 | HSD17B10 (0.57) | HSD17B10ADRA1ATAAR1HTR2AMTNR1A | |
| SCHEMBL3660479 | 0.87 | HSD17B10 (0.62) | HSD17B10ADRA1ATAAR1HTR2AMTNR1A | |
| SCHEMBL30861230 | 0.85 | HTR2A (0.65) | HSD17B10ADRA1ATAAR1HTR2AMTNR1A | |
| SCHEMBL5285095 | 0.85 | HTR2A (0.65) | HSD17B10ADRA1ATAAR1HTR2AMTNR1A | |
| Hydrochloric Acid SCHEMBL31327595 | 0.84 | HTR2A (0.63) | HSD17B10ADRA1ATAAR1HTR2AMTNR1A | |
| SCHEMBL22445010 | 0.83 | KIF11 (0.51) | MTNR1BKIF11SLC1A5 | |
| SCHEMBL8989272 | 0.82 | ADRA1A (0.63) | HSD17B10ADRA1ATAAR1HTR2AMTNR1A | |
| SCHEMBL16147892 | 0.81 | SLC1A5 (0.53) | TAAR1MTNR1AMTNR1BAOC3MEN1 | |
| SCHEMBL16147891 | 0.81 | SLC1A5 (0.53) | TAAR1MTNR1AMTNR1BAOC3MEN1 | |
| SCHEMBL28741601 | 0.81 | SLC1A5 (0.53) | TAAR1MTNR1AMTNR1BAOC3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2067786-A1 | Novel non selective analogs of somatostatin | ITALFARMACO S.p.A. (IT) | 2009-06-10 | — | — | EP | claimed |
| US-8937152-B2 | Non-selective somatostatin analogues | ITALFARMACO SPA (IT) | 2015-01-20 | — | — | US | disclosed |
| EP-2225271-B1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2013-07-31 | — | — | EP | disclosed |
| US-20100323964-A1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2010-12-23 | — | — | US | disclosed |
| EP-2225271-A2 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO S.p.A. (IT) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009071460-A2 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2009-06-11 | — | — | WO | disclosed |
| EP-2067786-A1 | Novel non selective analogs of somatostatin | ITALFARMACO S.p.A. (IT) | 2009-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323964-A1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | SSTR4, SSTR1, SSTR3 | HSD17B10 2349/4885ADRA1A 907/4885TAAR1 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.