Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031750 | 1.00 | HPGD (0.47) | HPGDMAPK1TSHRHSD17B10MEN1 | |
| SCHEMBL371151 | 1.00 | HPGD (0.47) | HPGDMAPK1TSHRHSD17B10MEN1 | |
| SCHEMBL366279 | 0.84 | MEN1 (0.64) | HPGDMEN1KMT2APDK2LMNA | |
| SCHEMBL20630215 | 0.81 | HPGD (0.52) | HPGDMAPK1TSHRMEN1KMT2A | |
| SCHEMBL21925269 | 0.81 | HPGD (0.52) | HPGDMAPK1TSHRMEN1KMT2A | |
| SCHEMBL18758195 | 0.79 | MEN1 (0.43) | MEN1KMT2APDK2LMNAALDH1A1 | |
| SCHEMBL17612732 | 0.79 | PDK2 (0.39) | HPGDMEN1KMT2APDK2LMNA | |
| SCHEMBL369666 | 0.77 | NPC1 (0.47) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL370715 | 0.77 | NPC1 (0.47) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL18758160 | 0.76 | KMT2A (0.43) | MEN1KMT2APDK2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313823-B1 | METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION | MICHELIN & CIE (FR) | 2022-11-09 | — | — | EP | disclosed |
| EP-3313822-B1 | METHOD FOR SYNTHESIZING AROMATIC OXIMES | MICHELIN & CIE (FR) | 2022-09-14 | — | — | EP | disclosed |
| EP-3313823-A1 | METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION | Compagnie Générale des Etablissements Michelin (FR) | 2018-05-02 | — | — | EP | disclosed |
| EP-2593437-B1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016207263-A1 | METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2016-12-29 | — | — | WO | disclosed |
| US-9394380-B2 | Graft polymer to which combined nitrogen molecules are grafted | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2016-07-19 | — | — | US | disclosed |
| EP-2593485-B1 | POLYMERS CRAFTET WITH AZOTIC MOLECULES | MICHELIN & CIE (FR) | 2016-03-23 | — | — | EP | disclosed |
| US-9045432-B2 | Nitrile oxide, nitrone, and nitrile imine compounds | ARKEMA FRANCE (FR) | 2015-06-02 | — | — | US | disclosed |
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2013-08-01 | — | — | US | disclosed |
| US-20130131279-A1 | GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED | Mchelin Recherche et Technique S.A. (CH) | 2013-05-23 | — | — | US | disclosed |
| EP-2593437-A1 | MOLECULES HAVING COMBINABLE GROUPS | Arkema France (FR) | 2013-05-22 | — | — | EP | disclosed |
| EP-2593485-A1 | GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED | Compagnie Générale des Etablissements Michelin (FR) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007441-A1 | GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007684-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | NCAPH, NCL, PARG | HPGD 2206/4885MAPK1 4439/4885TSHR 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.