Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890480 | 0.89 | MAPT (0.55) | LMNAALDH1A1MAPTL3MBTL1IDO1 | |
| SCHEMBL3658915 | 0.83 | HTR2A (0.51) | LMNAALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL3655717 | 0.78 | LMNA (0.47) | LMNAALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL641831 | 0.77 | HPGD (0.65) | LMNAALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2890291 | 0.74 | MAPT (0.59) | LMNAALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL14992159 | 0.73 | MAPT (0.53) | LMNAALDH1A1MAPTL3MBTL1IDO1 | |
| SCHEMBL13028326 | 0.73 | HTR2A (0.51) | LMNAALDH1A1MAPTL3MBTL1IDO1 | |
| SCHEMBL2890310 | 0.73 | HTR2A (0.51) | LMNAALDH1A1MAPTL3MBTL1IDO1 | |
| SCHEMBL14992720 | 0.73 | MAPT (0.56) | LMNAALDH1A1MAPTL3MBTL1IDO1 | |
| SCHEMBL28376698 | 0.71 | MAOB (0.66) | LMNAALDH1A1MAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220026-A2 | INHIBITORS OF 17BETA-HYDROXYSTEROID DEHYDROGENASE | Sterix Limited (GB) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009066072-A2 | COMPOUND | STERIX LIMITED (GB) | 2009-05-28 | — | — | WO | disclosed |