SCHEMBL3659563

SCHEMBL3659563

N[C@@H](CCC(=O)OP(=O)(O)O)C(=O)OP(=O)(O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.37
GRM8 O00222 2/20 0.33
GRM6 O15303 2/20 0.33
GRM7 Q14831 2/20 0.33
GRM4 Q14833 2/20 0.33
SLC1A1 P43005 2/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GSR P00390 1/20 0.33
CYP1A2 P05177 1/20 0.33
GRIK1 P39086 1/20 0.33
GRM5 P41594 1/20 0.33
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
GRIA4 P48058 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4751449 1.00 CA4 (0.37) CA4GRM8GRM6GRM7GRM4
Water SCHEMBL27732866 0.98 CA4 (0.35) CA4GRM8GRM6GRM7GRM4
SCHEMBL28235347 0.98 CA4 (0.35) CA4GRM8GRM6GRM7GRM4
SCHEMBL10671206 0.98 CA4 (0.35) CA4GRM8GRM6GRM7GRM4
Ammonia Solution, Strong SCHEMBL28656082 0.98 CA4 (0.35) CA4GRM8GRM6GRM7GRM4
SCHEMBL2351136 0.85 ALOX15 (0.50) CA4GRM8GRM6GRM7GRM4
SCHEMBL641432 0.85 GRM3 (0.52) GRM8GRM6GRM7GRM4SLC1A1
SCHEMBL12189719 0.85 GRM3 (0.52) GRM8GRM6GRM7GRM4SLC1A1
SCHEMBL641431 0.85 GRM3 (0.52) GRM8GRM6GRM7GRM4SLC1A1
SCHEMBL28137272 0.85 ALOX15 (0.50) CA4GRM8GRM6GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190284282-A1 STABLE PHARMACEUTICAL COMPOSITION DR. REDDY'S LABORATORIES LIMITED (IN) 2019-09-19 US claimed
EP-3402470-A1 STABLE PHARMACEUTICAL COMPOSITION Dr. Reddy's Laboratories Limited (IN) 2018-11-21 EP claimed
WO-2017122121-A1 STABLE PHARMACEUTICAL COMPOSITION DR. REDDY'S LABORATORIES LIMITED (IN) 2017-07-20 WO claimed
US-20190284282-A1 STABLE PHARMACEUTICAL COMPOSITION DR. REDDY'S LABORATORIES LIMITED (IN) 2019-09-19 US disclosed
EP-3402470-A1 STABLE PHARMACEUTICAL COMPOSITION Dr. Reddy's Laboratories Limited (IN) 2018-11-21 EP disclosed
WO-2017122121-A1 STABLE PHARMACEUTICAL COMPOSITION DR. REDDY'S LABORATORIES LIMITED (IN) 2017-07-20 WO disclosed
CN-105820163-A Substituted 1,3-miscellaneous azole compound, preparation method thereof, pharmaceutical composition containing substituted 1,3-miscellaneous azole compound and purpose thereof 中国医学科学院医药生物技术研究所 2016-08-03 CN disclosed
CN-104174071-A COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE ANGIODEVICE INTERNAT GMBH 2014-12-03 CN disclosed
EP-2235201-A1 METHODS AND COMPOSITIONS FOR ASSAYING HOMOCYSTEINE GENERAL ATOMICS (US) 2010-10-06 EP disclosed
WO-2009089106-A1 METHODS AND COMPOSITIONS FOR ASSAYING HOMOCYSTEINE GENERAL ATOMICS (US) 2009-07-16 WO disclosed
WO-2008137446-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASE TRUSTEES OF BOSTON UNIVERSITY (US) 2008-11-13 WO disclosed
CN-1897930-A Compositions and methods for treating contracture ANGIOTECH INT AG (CH) 2007-01-17 CN disclosed
CN-1333361-A Novel polypeptide--human L-3-phosphoserine phosphatase 10.01 and polynucleotide for encoding said polypeptide BODE GENE DEV CO LTD SHANGHAI (CN) 2002-01-30 CN disclosed
CN-1199402-A Method for production of magnesium pyridoxal-5'-phosphate glutamate and intermediate products obtained thereby STEIGERWALD ARZNEIMITTELWERK (DE) 1998-11-18 CN disclosed
US-4504515-A Process for preparing low-fat meat products and in particular sausages with high protein content HOHENESTER HERMANN (DE) 1985-03-12 US disclosed