Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM3 | Q14832 | 3/20 | 0.52 |
| ▸ | GRM8 | O00222 | 2/20 | 0.52 |
| ▸ | GRM6 | O15303 | 2/20 | 0.52 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189719 | 1.00 | GRM3 (0.52) | GRM3GRM8GRM6GRM7GRM4 | |
| SCHEMBL641431 | 1.00 | GRM3 (0.52) | GRM3GRM8GRM6GRM7GRM4 | |
| SCHEMBL13176585 | 0.85 | PEPD (0.39) | GRM3GRM8GRM6GRM7GRM4 | |
| SCHEMBL2351136 | 0.85 | ALOX15 (0.50) | GRM3GRM8GRM6GRM7GRM4 | |
| SCHEMBL3659563 | 0.85 | CA4 (0.37) | GRM3GRM8GRM6GRM7GRM4 | |
| SCHEMBL28137272 | 0.85 | ALOX15 (0.50) | GRM3GRM8GRM6GRM7GRM4 | |
| SCHEMBL4751449 | 0.85 | CA4 (0.37) | GRM3GRM8GRM6GRM7GRM4 | |
| Ammonia Solution, Strong SCHEMBL28656082 | 0.83 | CA4 (0.35) | GRM3GRM8GRM6GRM7GRM4 | |
| SCHEMBL10671206 | 0.83 | CA4 (0.35) | GRM3GRM8GRM6GRM7GRM4 | |
| Water SCHEMBL27732866 | 0.83 | CA4 (0.35) | GRM3GRM8GRM6GRM7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12480131-B2 | Tropane alkaloid (TA) producing non-plant host cells, and methods of making and using the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-11-25 | — | — | US | claimed |
| US-20250221954-A1 | METHODS TO TREAT, PREVENT, OR REDUCE HYPERAMMONEMIA | RUBIN DARREN ALEXANDER (US) | 2025-07-10 | — | — | US | claimed |
| EP-4314301-A1 | TROPANE ALKALOID TRANSPORTERS AND METHODS OF MAKING TROPANE ALKALOIDS USING THE SAME | The Board of Trustees of the Leland Stanford Junior University (US) | 2024-02-07 | — | — | EP | claimed |
| WO-2022204283-A1 | TROPANE ALKALOID TRANSPORTERS AND METHODS OF MAKING TROPANE ALKALOIDS USING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-09-29 | — | — | WO | claimed |
| US-12522842-B2 | Glutamine synthetase mutant having glufosinate resistance and application thereof and cultivation method therefor | GEVOTO LLC (CN) | 2026-01-13 | — | — | US | disclosed |
| EP-4647496-A1 | NOVEL PROMOTER AND USE THEREOF | CJ CheilJedang Corporation (KR) | 2025-11-12 | — | — | EP | disclosed |
| US-20250277226-A1 | IMPROVED BIOTECHNOLOGICAL METHOD FOR PRODUCING GUANIDINO ACETIC ACID (GAA) BY INACTIVATION OF AN AMINO ACID EXPORTER | EVONIK OPERATIONS GMBH (DE) | 2025-09-04 | — | — | US | disclosed |
| US-20250221954-A1 | METHODS TO TREAT, PREVENT, OR REDUCE HYPERAMMONEMIA | RUBIN DARREN ALEXANDER (US) | 2025-07-10 | — | — | US | disclosed |
| US-20250171790-A1 | METHOD FOR THE FERMENTATIVE PRODUCTION OF GUANIDINOACETIC ACID | EVONIK OPERATIONS GMBH (DE) | 2025-05-29 | — | — | US | disclosed |
| CN-119768521-A | Novel promoter and application thereof | CJ第一制糖株式会社 | 2025-04-04 | — | — | CN | disclosed |
| US-12065677-B2 | Method for the fermentative production of guanidinoacetic acid | EVONIK OPERATIONS GMBH (DE) | 2024-08-20 | — | — | US | disclosed |
| US-11999982-B2 | Method for the fermentative production of guanidinoacetic acid | EVONIK OPERATIONS GMBH (DE) | 2024-06-04 | — | — | US | disclosed |
| WO-2001053323-A2 | PLANTS TOLERANT OF ENVIRONMENTAL STRESS CONDITIONS, METHODS OF GENERATING SAME AND NOVEL POLYNUCLEOTIDE SEQUENCE UTILIZED THEREBY | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 2001-07-26 | — | — | WO | disclosed |
| WO-2001040268-A2 | BERYLLOFLUORIDE ANALOGUES OF ACYL PHOSPHATE POLYPEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-06-07 | — | — | WO | disclosed |
| EP-1066309-A1 | LIBRARIES OF EXPRESSIBLE GENE SEQUENCES | INVITROGEN CORPORATION (US) | 2001-01-10 | — | — | EP | disclosed |
| CN-1258736-A | Process for producing L--arginine | AJINOMOTO KK (JP) | 2000-07-05 | — | — | CN | disclosed |
| WO-1999051620-A1 | LIBRARIES OF EXPRESSIBLE GENE SEQUENCES | INVITROGEN CORPORATION (US) | 1999-10-14 | — | — | WO | disclosed |
| US-5695960-A | Hippuricase gene | CHAN VOON LOONG (CA) | 1997-12-09 | — | — | US | disclosed |
| US-5639950-A | GENETIC ENGINEERING | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5344923-A | Improved salt and drought resistance for plants | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1994-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250277226-A1 | IMPROVED BIOTECHNOLOGICAL METHOD FOR PRODUCING GUANIDINO ACETIC ACID (GAA) BY INACTIVATION OF AN AMINO ACID EXPORTER | GDA, GAA, AGXT | GRM3 941/4885GRM8 1241/4885GRM6 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.